930695
4-Aminomethyl-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione hydrochloride
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 444287-40-5
Synonym(S): 1H-Isoindole-1,3(2H)-dione, 4-(aminomethyl)-2-(2,6-dioxo-3-piperidinyl) hydrochloride
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 930695-50-MG | In Stock | ₹ 19,470.00 |
930695 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 19,470.00
GST (18%): ₹ 3,504.60
Total Price: ₹ 22,974.60
Quality Level
100
Assay
≥95%
form
powder
reaction suitability
reagent type: ligand
functional group
amine
storage temp.
2-8°C
SMILES string
NCC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Thalidomide-CH2NH2 (hydrochloride) | ChemScene | ₹ 19,580.00 - ₹ 54,290.00 | |
 | 444287-40-5 | 1H-Isoindole-1,3(2H)-dione,4-(aminomethyl)-2-(2,6-dioxo-3-piperidinyl)-, monohydrochloride | A2B Chem | ₹ 31,684.00 |
Related Products
Description
- Application: 4-Aminomethyl-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione hydrochloride is a functionalized Cereblon ligand used for development of protein degrader building blocks. Contains a terminal amine group, allowing rapid conjugation of carboxyl containing linkers. A basic building block for development of a protein degrader library.
- Other Notes: Targeted Protein Degradation by Small MoleculesDestruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug Discovery Impact of linker length on the activity of PROTACs
- Legal Information: PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 1B
WGK
WGK 3
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Quality Level: 100
Assay: ≥95%
form: powder
reaction suitability: reagent type: ligand
functional group: amine
storage temp.: 2-8°C
SMILES string: NCC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1
Quality Level:
100
Assay:
≥95%
form:
powder
reaction suitability:
reagent type: ligand
functional group:
amine
storage temp.:
2-8°C
SMILES string:
NCC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1
Quality Level: 100
Assay: ≥95.0%
form: powder
reaction suitability: __
functional group: carboxylic acid
storage temp.: 2-8°C
SMILES string: __
Quality Level:
100
Assay:
≥95.0%
form:
powder
reaction suitability:
__
functional group:
carboxylic acid
storage temp.:
2-8°C
SMILES string:
__
Quality Level: 100
Assay: ≥95%
form: powder
reaction suitability: __
functional group: amine
storage temp.: 2-8°C
SMILES string: O=C1NC(C(CC1)N2C(C3=CC=C(C=C3C2=O)OC4CCNCC4)=O)=O
Quality Level:
100
Assay:
≥95%
form:
powder
reaction suitability:
__
functional group:
amine
storage temp.:
2-8°C
SMILES string:
O=C1NC(C(CC1)N2C(C3=CC=C(C=C3C2=O)OC4CCNCC4)=O)=O
Quality Level: 100
Assay: ≥95.0%
form: powder
reaction suitability: __
functional group: hydroxyl
storage temp.: 2-8°C
SMILES string: O=C1NC(=O)C(N2C(=O)C=3C=CC=C(C#CCCO)C3C2)CC1
Quality Level:
100
Assay:
≥95.0%
form:
powder
reaction suitability:
__
functional group:
hydroxyl
storage temp.:
2-8°C
SMILES string:
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(C#CCCO)C3C2)CC1