H7666
Interleukin-12 human
HumanKine®, recombinant, expressed in HEK 293 cells, suitable for cell culture, endotoxin, tested
Manufacturer: Sigma Aldrich
Synonym(S): IL-12
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | H7666-10-μG | In Stock | ₹ 57,908.70 |
H7666 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 57,908.70
GST (18%): ₹ 10,423.566
Total Price: ₹ 68,332.266
biological source
human
Quality Level
200
recombinant
expressed in HEK 293 cells
Assay
≥95% (SDS-PAGE)
form
lyophilized
potency
≤2 ng/mL EC50
mol wt
dimer 57 kDa (glycosylated)
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
Related Products
Description
- Application: Interleukin-12 (IL-12) human has been used to study IL-12 mediated enhancement of IL-12Rβ2 (IL-12 receptor) expression.[1]
- Biochem/physiol Actions: Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12, or Natural Killer Cell Stimulatory Factor (NKSF), is a 75 kDa disulfide-linked heterodimer of a 35 kDa subunit and 40 kDa subunit. IL-12 is produced predominantly by monocytes and NK cells and induces T cells and NK cells to produce IFN-γ. Human IL-12 is not active on mouse cells, but murine IL-12 is active on both murine and human lymphocytes. The biological activity of recombinant human IL-12 was measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. IL-12 has anti-angiogenic properties.
- Physical form: lyophilized from a 0.2 μm filtered solution of PBS
- Analysis Note: The specific activity was determined by the dose-dependent release of IFN-γ from the human NK92 cell line in presence of 20 ng/mL rIL-2.
- Legal Information: HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
SAFETY INFORMATION
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: human
Quality Level: 200
recombinant: expressed in HEK 293 cells
Assay: ≥95% (SDS-PAGE)
form: lyophilized
potency: ≤2 ng/mL EC50
mol wt: dimer 57 kDa (glycosylated)
packaging: pkg of 10 μg
technique(s): cell culture | mammalian: suitable
impurities: endotoxin, tested
biological source:
human
Quality Level:
200
recombinant:
expressed in HEK 293 cells
Assay:
≥95% (SDS-PAGE)
form:
lyophilized
potency:
≤2 ng/mL EC50
mol wt:
dimer 57 kDa (glycosylated)
packaging:
pkg of 10 μg
technique(s):
cell culture | mammalian: suitable
impurities:
endotoxin, tested
biological source: __
Quality Level: 200
recombinant: __
Assay: ≥99% (TLC)
form: powder
potency: __
mol wt: __
packaging: __
technique(s): ligand binding assay: suitable
impurities: __
biological source:
__
Quality Level:
200
recombinant:
__
Assay:
≥99% (TLC)
form:
powder
potency:
__
mol wt:
__
packaging:
__
technique(s):
ligand binding assay: suitable
impurities:
__
biological source: __
Quality Level: 200
recombinant: __
Assay: ≥99% (TLC)
form: powder
potency: __
mol wt: __
packaging: __
technique(s): ligand binding assay: suitable
impurities: __
biological source:
__
Quality Level:
200
recombinant:
__
Assay:
≥99% (TLC)
form:
powder
potency:
__
mol wt:
__
packaging:
__
technique(s):
ligand binding assay: suitable
impurities:
__
biological source: Streptomyces hygroscopicus
Quality Level: 200
recombinant: __
Assay: __
form: lyophilized powder
potency: __
mol wt: __
packaging: __
technique(s): __
impurities: __
biological source:
Streptomyces hygroscopicus
Quality Level:
200
recombinant:
__
Assay:
__
form:
lyophilized powder
potency:
__
mol wt:
__
packaging:
__
technique(s):
__
impurities:
__