H7791

Interleukin-17A human

IL-17A, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): CTLA-8, IL-17

Select a Size

Pack Size SKU Availability Price
10 μG H7791-10-μG In Stock ₹ 21,756.00

H7791 - 10 μG

₹ 21,756.00

In Stock

Quantity

1

Base Price: ₹ 21,756.00

GST (18%): ₹ 3,916.08

Total Price: ₹ 25,672.08

biological source

human

Quality Level

100

recombinant

expressed in HEK 293 cells

Assay

≥95% (SDS-PAGE)

form

lyophilized powder

potency

≤2 ng/mL EC50

quality

endotoxin tested

mol wt

dimer 30-35 kDa (glycosylated)

packaging

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

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Description

  • Biochem/physiol Actions: IL-17, initially known as CTLA-8, is a T cell-expressed polypeptide that appears to be involved in the regulation of the hematopoietic system. IL-17 has been shown to induce IL-6, IL-8, and G-CSF production by fibroblasts; all of these cytokines have demonstrated effects on hematopoiesis.
  • Physical form: Lyophilized from a 0.2 μm filtered solution of 10 mM Tris-HCl pH 7.4+ 250 mM NaCl
  • Preparation Note: HumanKine Interleukin-17A (IL-17A), expressed in human HEK 293 cells, is a glycosylated homodimer with an apparent molecular mass of 30-35 kDa due to glycosylation. Production in human 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
  • Analysis Note: The specific activity was determined by the dose-dependent induction of IL-6 secretion from NDHF adult fibroblasts.
  • Legal Information: HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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biological source:
human

Quality Level:
100

recombinant:
expressed in HEK 293 cells

Assay:
≥95% (SDS-PAGE)

form:
lyophilized powder

potency:
≤2 ng/mL EC50

quality:
endotoxin tested

mol wt:
dimer 30-35 kDa (glycosylated)

packaging:
pkg of 10 μg

technique(s):
cell culture | mammalian: suitable

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