H8041
Interleukin-23 human
IL-23, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): Human IL-23, IL-23 Cytokine, Interleukin 23
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 μG | H8041-5-μG | In Stock | ₹ 43,833.90 |
| 10 μG | H8041-10-μG | In Stock | ₹ 81,729.30 |
| 5 X 10 μG | H8041-5-X-10-μG | In Stock | ₹ 2,51,059.80 |
H8041 - 5 μG
In Stock
Quantity
1
Base Price: ₹ 43,833.90
GST (18%): ₹ 7,890.102
Total Price: ₹ 51,724.002
biological source
human
Quality Level
100
recombinant
expressed in HEK 293 cells
Assay
≥95% (SDS-PAGE)
form
lyophilized powder
potency
≤2 ng/mL EC50
quality
endotoxin tested
mol wt
dimer 55 kDa (glycosylated)
packaging
pkg of 5X10 μgpkg of 10 μgpkg of 5 μg
technique(s)
cell culture | mammalian: suitable
Related Products
Description
- General description: HumanKine interleukin-23 (IL-23) is expressed as a heterodimeric 55 kDa cytokine composed of two glycosylated and disulfide linked subunits (p40 cystine linked to p19). Production in human HEK 293 cells offers authentic glycosylation. Cytokines produced in Sf9 or Sf21 cells have post-translational modifications, which are not human-like. Interleukin-23 (IL-23) is a pro-inflammatory cytokine. It is mostly synthesized by activated dendritic cells and macrophages.[1] It is a 20.7kDa protein with 189 amino acids. IL-23 is mostly expressed on activated/memory T cells and natural killer (NK) cells. This gene is located on human chromosome 12q13.3.[2]
- Biochem/physiol Actions: Interleukin-23 (IL-23) plays a major role in cutaneous immune-mediated inflammatory diseases like psoriasis, allergic contact dermatitis and atopic dermatitis. It is involved in cellular immunity, driving the expansion, stabilization and survival of Th17 cells.[1]
- Analysis Note: The specific activity was determined by the dose-dependent secretion of h-IFN-γ or IL-8 from human PBMC.
- Legal Information: HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
SAFETY INFORMATION
WGK
WGK 1
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biological source: human
Quality Level: 100
recombinant: expressed in HEK 293 cells
Assay: ≥95% (SDS-PAGE)
form: lyophilized powder
potency: ≤2 ng/mL EC50
quality: endotoxin tested
mol wt: dimer 55 kDa (glycosylated)
packaging: pkg of 5X10 μgpkg of 10 μgpkg of 5 μg
technique(s): cell culture | mammalian: suitable
biological source:
human
Quality Level:
100
recombinant:
expressed in HEK 293 cells
Assay:
≥95% (SDS-PAGE)
form:
lyophilized powder
potency:
≤2 ng/mL EC50
quality:
endotoxin tested
mol wt:
dimer 55 kDa (glycosylated)
packaging:
pkg of 5X10 μgpkg of 10 μgpkg of 5 μg
technique(s):
cell culture | mammalian: suitable
biological source: __
Quality Level: 200
recombinant: __
Assay: __
form: (1:1 suspension in a 30% ethanol solution)
potency: __
quality: __
mol wt: __
packaging: __
technique(s): protein purification: suitable
biological source:
__
Quality Level:
200
recombinant:
__
Assay:
__
form:
(1:1 suspension in a 30% ethanol solution)
potency:
__
quality:
__
mol wt:
__
packaging:
__
technique(s):
protein purification: suitable
biological source: __
Quality Level: 400
recombinant: __
Assay: __
form: liquid
potency: __
quality: __
mol wt: __
packaging: __
technique(s): cell culture | mammalian: suitable
biological source:
__
Quality Level:
400
recombinant:
__
Assay:
__
form:
liquid
potency:
__
quality:
__
mol wt:
__
packaging:
__
technique(s):
cell culture | mammalian: suitable
biological source: __
Quality Level: 400
recombinant: __
Assay: __
form: liquid
potency: __
quality: __
mol wt: __
packaging: __
technique(s): cell culture | mammalian: suitable
biological source:
__
Quality Level:
400
recombinant:
__
Assay:
__
form:
liquid
potency:
__
quality:
__
mol wt:
__
packaging:
__
technique(s):
cell culture | mammalian: suitable