94675

Valinomycin

≥99.0% (TLC)

Manufacturer: Sigma Aldrich

CAS Number: 2001-95-8

Synonym(S): Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid

Select a Size

Pack Size SKU Availability Price
10 MG 94675-10-MG In Stock ₹ 11,322.95
100 MG 94675-100-MG In Stock ₹ 58,195.20
500 MG 94675-500-MG In Stock ₹ 1,86,114.23

94675 - 10 MG

₹ 11,322.95

In Stock

Quantity

1

Base Price: ₹ 11,322.95

GST (18%): ₹ 2,038.131

Total Price: ₹ 13,361.081

Quality Level

200

Assay

≥99.0% (TLC)

form

powder

mp

187-190 °C

antibiotic activity spectrum

mycobacteria

Mode of action

cell membrane | interferes

storage temp.

2-8°C

SMILES string

CC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)[C@@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C

InChI

1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t31-,32-,33-,34-,35+,36+,37-,38-,39-,40+,41+,42+/m0/s1

InChI key

FCFNRCROJUBPLU-RPUZOQEISA-N

Other Options

Image Product Name Manufacturer Price Range
60403
Potassium ionophore I
Supelco ₹ 64,148.95
V0627
Valinomycin
Sigma Aldrich ₹ 10,543.55 - ₹ 2,22,302.20
V3639
Valinomycin
Sigma Aldrich ₹ 9,948.18

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Description

  • General description: Chemical structure: peptide
  • Application: Valinomycin has been used as an internal standard in the cytotoxicity assay for the detection of cereulide produced by emetic Bacillus cereus.[4] It has also been used in the measurement of the electrogenicity of bile salt/H+ antiport in Escherichia coli.[5]
  • Biochem/physiol Actions: K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction.
  • Other Notes: Review[7]

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H300 + H310

Precautionary Statements

P262 - P264 - P280 - P301 + P310 - P302 + P352 + P310 - P361 + P364

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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94675

≥99.0% (TLC)...


Quality Level:
200

Assay:
≥99.0% (TLC)

form:
powder

mp:
187-190 °C

antibiotic activity spectrum:
mycobacteria

Mode of action:
cell membrane | interferes

storage temp.:
2-8°C

SMILES string:
CC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)[C@@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C

InChI:
1S/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t31-,32-,33-,34-,35+,36+,37-,38-,39-,40+,41+,42+/m0/s1

InChI key:
FCFNRCROJUBPLU-RPUZOQEISA-N

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