7-Aminoactinomycin D
~97% (HPLC), powder, fluorescent DNA stain
Manufacturer: Sigma Aldrich
CAS Number: 7240-37-1
Synonym(S): 7-AAD
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | A9400-1-MG | In Stock | ₹ 25,287.20 |
| 5 MG | A9400-5-MG | In Stock | ₹ 99,676.60 |
A9400 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 25,287.20
GST (18%): ₹ 4,551.696
Total Price: ₹ 29,838.896
Assay
~97% (HPLC)
Quality Level
300
form
powder
color
red to very dark purple
antibiotic activity spectrum
neoplastics
Mode of action
DNA synthesis | interferes
storage temp.
2-8°C
SMILES string
CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2cc(N)c(C)c3OC4=C(C)C(=O)C(N)=C(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)C4=Nc23)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]7CCCN7C1=O
InChI
1S/C62H87N13O16/c1-26(2)42-59(85)74-21-17-19-36(74)57(83)70(13)24-38(76)72(15)48(28(5)6)61(87)89-32(11)44(55(81)66-42)68-53(79)34-23-35(63)30(9)51-46(34)65-47-40(41(64)50(78)31(10)52(47)91-51)54(80)69-45-33(12)90-62(88)49(29(7)8)73(16)39(77)25-71(14)58(84)37-20-18-22-75(37)60(86)43(27(3)4)67-56(45)82/h23,26-29,32-33,36-37,42-45,48-49H,17-22,24-25,63-64H2,1-16H3,(H,66,81)(H,67,82)(H,68,79)(H,69,80)/t32-,33-,36+,37+,42-,43-,44+,45+,48+,49?/m1/s1
InChI key
YXHLJMWYDTXDHS-SGILFZQNSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Enzo Life Sciences 7-Aminoactinomycin D (1mg). CAS: 7240-37-1 | Enzo Life Sciences | ₹ 13,971.95 | |
 | Tocris™ 7-Aminoactinomycin D | Tocris™ | ₹ 2,069.70 | |
| | Aat Bioquest 7-AAD [7-Aminoactinomycin D] CAS 7240-37-1 (1 mg) | Aat Bioquest | ₹ 9,035.14 | |
 | Sigma Aldrich Fine Chemicals Biosciences 7-Aminoactinomycin D | 7240-37-1 | MFCD00077295 | 1mg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 21,381.44 | |
 | Sigma Aldrich Fine Chemicals Biosciences 7-Aminoactinomycin D ~97% (HPLC), powder | 7240-37-1 | MFCD00077295 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 92,177.21 | |
 | 7-Aminoactinomycin D | Sigma Aldrich | ₹ 25,287.20 - ₹ 99,676.60 | |
 | 7240-37-1 | 7-Aminoactinomycin d | A2B Chem | ₹ 7,871.52 - ₹ 33,368.40 |
Related Products
Description
- General description: 7-Aminoactinomycin D (7-ADD), an analog of actinomycin D (AD) is a membrane-impermeable red fluorescent DNA dye. It can selectively bind GC regions of DNA. 7-ADD is used in flow cytometry to differentiate between viable, apoptotic, and late apoptotic/dead cells. This DNA stain finds its application in chromosome analysis, cell cycle studies, and quantification of apoptosis.
- Application: 7-Aminoactinomycin D has been used:for nuclei visualization in mouse tail skinas a nuclear stain in imaging flow cytometry for nucleus-protein colocalizationin flow cytometry to determine the level of CD16 (Fc gamma III receptor) and CD32 (Fc gamma II receptor) in epidermal cells
- Features and Benefits: This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
Assay: ~97% (HPLC)
Quality Level: 300
form: powder
color: red to very dark purple
antibiotic activity spectrum: neoplastics
Mode of action: DNA synthesis | interferes
storage temp.: 2-8°C
SMILES string: CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2cc(N)c(C)c3OC4=C(C)C(=O)C(N)=C(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)C4=Nc23)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]7CCCN7C1=O
InChI: 1S/C62H87N13O16/c1-26(2)42-59(85)74-21-17-19-36(74)57(83)70(13)24-38(76)72(15)48(28(5)6)61(87)89-32(11)44(55(81)66-42)68-53(79)34-23-35(63)30(9)51-46(34)65-47-40(41(64)50(78)31(10)52(47)91-51)54(80)69-45-33(12)90-62(88)49(29(7)8)73(16)39(77)25-71(14)58(84)37-20-18-22-75(37)60(86)43(27(3)4)67-56(45)82/h23,26-29,32-33,36-37,42-45,48-49H,17-22,24-25,63-64H2,1-16H3,(H,66,81)(H,67,82)(H,68,79)(H,69,80)/t32-,33-,36+,37+,42-,43-,44+,45+,48+,49?/m1/s1
InChI key: YXHLJMWYDTXDHS-SGILFZQNSA-N
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form: powder
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