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SRP4037

FGF-2 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

Manufacturer: Sigma Aldrich

Synonym(S): FGF-2, Fibroblast Growth Factor-basic, HBGF-2, Prostatropin

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Pack Size SKU Availability Price
50 μG SRP4037-50-μG In Stock ₹ 39,549.30

SRP4037 - 50 μG

₹ 39,549.30

In Stock

Quantity

1

Base Price: ₹ 39,549.30

GST (18%): ₹ 7,118.874

Total Price: ₹ 46,668.174

biological source

human

recombinant

expressed in E. coli

Assay

≥95% (HPLC)≥95% (SDS-PAGE)

form

lyophilized

mol wt

~17.2 kDa

packaging

pkg of 50 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

NCBI accession no.

NM_002006

UniProt accession no.

P09038

Description

  • General description: The gene FGF2 (fibroblast growth factor 2) is mapped to human chromosome 4q28.[1] FGF-2 is a basic heparin binding growth factor.[2] The recombinant human FGF-2 is a 17.2kDa protein containing 154 amino acid residues. It is also referred to as BFGF (basic fibroblast growth factor).
  • Application: FGF-2 human has been used:as medium supplement for E9.5 neuroepithelial cell culture[3] as a component in the neurobasal growth mediumin growing embryonic neural stem/progenitor cells (NSPCs) in a 2D culture[4]
  • Biochem/physiol Actions: FGF2 (fibroblast growth factor 2, also referred to as BFGF (basic fibroblast growth factor)) interacts with FGFR1 (fibroblast growth factor receptor 1), FGFR2 and FGFR3.[6] It stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells.[7][8][9] FGF2 also determines the fate of neural precursor cells and promotes neuronal axon regeneration. It plays an important role in spinal cord injury repair.[10] FGF2 is known to stimulate angiogenesis and is associated with cancer development.[11] High levels of FGF2 are present in the kidney of children with HIV (human immunodeficiency virus)-renal diseases.[12] The FGF2 mRNA is a target of miRNA miR-503.[13]
  • Physical form: Lyophilized from a 1 mg/ml solution of 5 mM Tris pH 7.6 plus 150 mM NaCl.
  • Reconstitution: Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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