SRP4739

PLGF-1 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

Manufacturer: Sigma Aldrich

Synonym(S): PGF, PIGF, PLGF 1, Placenta Growth Factor-1

Select a Size

Pack Size SKU Availability Price
25 μG SRP4739-25-μG In Stock ₹ 34,943.10

SRP4739 - 25 μG

₹ 34,943.10

In Stock

Quantity

1

Base Price: ₹ 34,943.10

GST (18%): ₹ 6,289.758

Total Price: ₹ 41,232.858

biological source

human

recombinant

expressed in E. coli

Assay

≥95% (HPLC)≥95% (SDS-PAGE)

form

lyophilized

mol wt

~29.7 kDa

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

NCBI accession no.

AAD30179

UniProt accession no.

P49763

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Description

  • General description: PLGF (placental growth factor), originally identified in human placenta, is a member of the VEGF (vascular endothelial growth factor) family. This protein is predominantly expressed in placenta, and also shows expression in heart, thyroid, lung and skeletal muscle. It is alternatively spliced to produce three isoforms in humans namely, PLGF1, PLGF2 and PLGF3.[1]Recombinant mouse PLGF is a disulfide-linked homodimer containing two 142 amino acid polypeptide chains.
  • Biochem/physiol Actions: PLGF (placental growth factor) is involved in angiogenesis, but does not play an essential role in angiogenesis during reproduction and development. However, inactivation of this gene in pathological conditions such as, ischemia, inflammation and cancer, results in impaired angiogenesis. Preclinical studies show that this protein might be a therapeutic target for treatment of angiogenesis and inflammation related disorders.[1] In acute coronary syndrome (ACS) patients, increased levels of PLGF are linked with obstructive sleep apnea (OSA) and short-term adverse outcomes.[2]
  • Physical form: Sterile filtered and lyophilized with no additives.
  • Reconstitution: Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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SRP4739

recombinant, expressed in E. coli, ...


biological source:
human

recombinant:
expressed in E. coli

Assay:
≥95% (HPLC)≥95% (SDS-PAGE)

form:
lyophilized

mol wt:
~29.7 kDa

packaging:
pkg of 25 μg

storage condition:
avoid repeated freeze/thaw cycles

impurities:
endotoxin, tested

NCBI accession no.:
AAD30179

UniProt accession no.:
P49763

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form:
lyophilized

mol wt:
~13 kDa

packaging:
pkg of 20 μg

storage condition:
avoid repeated freeze/thaw cycles

impurities:
endotoxin, tested

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UniProt accession no.:
Q9NR23

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