SRP4171
IL-15 from mouse
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Manufacturer: Sigma Aldrich
Synonym(S): IL 15, IL-T, Interleukin 15
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | SRP4171-10-μG | In Stock | ₹ 35,830.80 |
SRP4171 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 35,830.80
GST (18%): ₹ 6,449.544
Total Price: ₹ 42,280.344
biological source
mouse
recombinant
expressed in E. coli
Assay
≥98% (HPLC)≥98% (SDS-PAGE)
form
lyophilized
mol wt
~13.3 kDa
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
NCBI accession no.
P48346
UniProt accession no.
P48346
Related Products
Description
- General description: IL15 (interleukin 15) protein is a short-chain α-helical bundle type 1 T cell-stimulating cytokine. It is a pleiotropic cytokine belonging to the cytokine receptor γ chain family, and is expressed by dendritic cells (DCs), epithelial cells, macrophages, monocytes, and fibroblasts. IL15, along with its receptor IL15Rα, are co-expressed majorly by activated monocytes and DCs (dendritic cells).[1][2][3] Recombinant mouse IL-15 is a 13.3 kDa protein containing 115 amino acid residues.
- Biochem/physiol Actions: IL15 (interleukin 15) and IL2 are the only two known cytokine till date that bind to T-cells through IL-2Rβ (IL2 receptorβ). It interacts with lymphocytes via the heterotrimeric IL-15 receptor (IL-15R) composed of IL-15Rα, IL-2 receptor beta (IL-2Rβ), and IL-2 receptor gamma (IL-2Rγ). Since, IL-2R and IL-15R have common subunits, it is supposed that IL2 and IL15 perform similar functions, such as induction of lymphocyte activation and proliferation in vitro, and apoptosis of activated lymphocytes (AICD). However, unlike IL2, IL15 mimics the function of IFN I (interferon) by potently and selectively activating memory-phenotype CD44hi CD8+ cells.[4][5]
- Physical form: Lyophilized from 10 mM Tris, pH 8.0.
- Reconstitution: Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
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biological source: mouse
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
mol wt: ~13.3 kDa
packaging: pkg of 10 μg
storage condition: avoid repeated freeze/thaw cycles
impurities: endotoxin, tested
NCBI accession no.: P48346
UniProt accession no.: P48346
biological source:
mouse
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
mol wt:
~13.3 kDa
packaging:
pkg of 10 μg
storage condition:
avoid repeated freeze/thaw cycles
impurities:
endotoxin, tested
NCBI accession no.:
P48346
UniProt accession no.:
P48346
biological source: mouse
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
mol wt: ~8.5 kDa
packaging: pkg of 10 μg
storage condition: __
impurities: endotoxin, tested
NCBI accession no.: Q9Z121
UniProt accession no.: __
biological source:
mouse
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
mol wt:
~8.5 kDa
packaging:
pkg of 10 μg
storage condition:
__
impurities:
endotoxin, tested
NCBI accession no.:
Q9Z121
UniProt accession no.:
__
biological source: mouse
recombinant: expressed in E. coli
Assay: ≥98% (SDS-PAGE)
form: lyophilized
mol wt: ~13.4 kDa
packaging: pkg of 20 μg
storage condition: __
impurities: endotoxin, tested
NCBI accession no.: P01139
UniProt accession no.: __
biological source:
mouse
recombinant:
expressed in E. coli
Assay:
≥98% (SDS-PAGE)
form:
lyophilized
mol wt:
~13.4 kDa
packaging:
pkg of 20 μg
storage condition:
__
impurities:
endotoxin, tested
NCBI accession no.:
P01139
UniProt accession no.:
__
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
mol wt: ~27 kDa
packaging: pkg of 50 μg
storage condition: avoid repeated freeze/thaw cycles
impurities: endotoxin, tested
NCBI accession no.: X80915
UniProt accession no.: __
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
mol wt:
~27 kDa
packaging:
pkg of 50 μg
storage condition:
avoid repeated freeze/thaw cycles
impurities:
endotoxin, tested
NCBI accession no.:
X80915
UniProt accession no.:
__