SRP6552

TGF-β3 from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

Manufacturer: Sigma Aldrich

Synonym(S): Transforming growth factor beta-3

Select a Size

Pack Size SKU Availability Price
5 μG SRP6552-5-μG In Stock ₹ 44,858.80

SRP6552 - 5 μG

₹ 44,858.80

In Stock

Quantity

1

Base Price: ₹ 44,858.80

GST (18%): ₹ 8,074.584

Total Price: ₹ 52,933.384

biological source

mouse

recombinant

expressed in E. coli

Assay

≥98% (SDS-PAGE)

form

liquid

mol wt

25.5 kDa

packaging

pkg of 5 μgpkg of 50 μgpkg of 500 μg

concentration

0.25 mg/mL

impurities

≤1 EU/μg endotoxin (LAL test)

UniProt accession no.

P04202

shipped in

dry ice

Description

  • General description: TGFβ3 (transforming growth factor β3) is one of the three isoforms of mammalian TGFβ, and all the isoforms share high sequence similarity at the active domains, with TGFβ3 showing highest similarity with TGFβ1.[1]Recombinant mouse TGF-β3 is a non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains, with a total molecular weight of 25.5kDa.
  • Biochem/physiol Actions: TGFβ3 (transforming growth factor β3) shows higher expression levels during late stage tumors, and hence, is thought to be associated with tumorigenesis. However, studies also show that in skin, breast, oral and gastric mucosa and other types of tissue, this protein confers protection against tumorigenesis. It plays crucial role in the development of systems such as heart, breast and lung. It is essential for mouse embryonic palate fusion, as inactivation results in non-fusion of palatal shelves.[1] This protein plays a crucial role in orofacial development and is essential for excisional wound repair in vivo.[4]
  • Physical form: 0.25 mg/mL solution containing 20% ethanol and 0.12% acetic acid (AcOH) .

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

does not flash

Flash Point(C)

does not flash

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