SRP8035

IL-36α mouse

recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)

Manufacturer: Sigma Aldrich

Synonym(S): Interleukin-1 family member 6, Interleukin-1 homolog 1, Interleukin-1α, Interleukin-36α

Select a Size

Pack Size SKU Availability Price
10 μG SRP8035-10-μG In Stock ₹ 50,283.00

SRP8035 - 10 μG

₹ 50,283.00

In Stock

Quantity

1

Base Price: ₹ 50,283.00

GST (18%): ₹ 9,050.94

Total Price: ₹ 59,333.94

biological source

mouse

recombinant

expressed in E. coli

conjugate

untagged

Assay

>95% (SDS-PAGE)

form

lyophilized

mol wt

~17 kDa

packaging

pkg of 10 μg

impurities

<0.01 EU/μg endotoxin, tested

UniProt accession no.

Q9JLA2

shipped in

wet ice

Description

  • General description: IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
  • Physical form: Lyophilized from PBS.
  • Reconstitution: Reconstitute with 100 μL deionized water.
  • Other Notes: IL-36alpha (mouse) (aa 8-160) is untagged.

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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