T5425
Transforming Growth Factor-β3 human
TGF-β3, recombinant, expressed in baculovirus infected Sf21 cells, powder, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): hTGF-β3, TGF-β3
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 2 μG | T5425-2-μG | In Stock | ₹ 53,345.60 |
T5425 - 2 μG
In Stock
Quantity
1
Base Price: ₹ 53,345.60
GST (18%): ₹ 9,602.208
Total Price: ₹ 62,947.808
biological source
human
Quality Level
100
recombinant
expressed in baculovirus infected Sf21 cells
Assay
≥97% (SDS-PAGE)
form
powder
potency
0.01-0.09 ng/mL ED50/EC50
quality
endotoxin tested
mol wt
predicted mol wt ~25 kDa
packaging
pkg of 2 μg
storage condition
avoid repeated freeze/thaw cycles
Related Products
Description
- General description: The TGFβ3 (transforming Growth Factor-β3) gene is mapped to human chromosome 14q24.3.[1]
- Application: Transforming Growth Factor-β3 human has been used to study the role of TGF-β3 in healing tendon-to-bone insertion and in chondrogenic differentiation.[2][3]
- Biochem/physiol Actions: TGF-β (transforming growth factor-β3) isoforms are significantly involved in inducing inflammatory responses. It is associated with vascular diseases, wound healing and ameliorating effect in venous leg ulcer. TGF-β3 has an antagonistic effect on TGF-β1 and reduces the degree of collagen type I deposition and fibroblast differentiation. As a result TGF-β3 might lead to ulcer chronicity due to hindered myofibroblasts formation.[4] TGF-β is a key player in tumor formation and progression. Increased TGF-β3 expression is observed in cancer and adipose tissue fibrosis.[5][6] TGF-β3 is crucial in tissue regeneration and scarless tissue repair.[7]
- Physical form: Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% trifluoroacetic acid containing 50 μg bovine serum albumin per 1 μg of cytokine.
- Analysis Note: The biological activity is measured by its ability to inhibit the IL-4-dependent proliferation of mouse HT-2 cells.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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biological source: human
Quality Level: 100
recombinant: expressed in baculovirus infected Sf21 cells
Assay: ≥97% (SDS-PAGE)
form: powder
potency: 0.01-0.09 ng/mL ED50/EC50
quality: endotoxin tested
mol wt: predicted mol wt ~25 kDa
packaging: pkg of 2 μg
storage condition: avoid repeated freeze/thaw cycles
biological source:
human
Quality Level:
100
recombinant:
expressed in baculovirus infected Sf21 cells
Assay:
≥97% (SDS-PAGE)
form:
powder
potency:
0.01-0.09 ng/mL ED50/EC50
quality:
endotoxin tested
mol wt:
predicted mol wt ~25 kDa
packaging:
pkg of 2 μg
storage condition:
avoid repeated freeze/thaw cycles
biological source: __
Quality Level: 100
recombinant: __
Assay: 99%
form: __
potency: __
quality: __
mol wt: __
packaging: __
storage condition: __
biological source:
__
Quality Level:
100
recombinant:
__
Assay:
99%
form:
__
potency:
__
quality:
__
mol wt:
__
packaging:
__
storage condition:
__
biological source: __
Quality Level: 200
recombinant: __
Assay: ≥99%
form: crystalline powder
potency: __
quality: __
mol wt: __
packaging: __
storage condition: __
biological source:
__
Quality Level:
200
recombinant:
__
Assay:
≥99%
form:
crystalline powder
potency:
__
quality:
__
mol wt:
__
packaging:
__
storage condition:
__
biological source: __
Quality Level: 100
recombinant: __
Assay: 99%
form: powder or crystals
potency: __
quality: __
mol wt: __
packaging: __
storage condition: __
biological source:
__
Quality Level:
100
recombinant:
__
Assay:
99%
form:
powder or crystals
potency:
__
quality:
__
mol wt:
__
packaging:
__
storage condition:
__