V3388

Vascular Endothelial Growth Factor (aa 207-318) human

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

Manufacturer: Sigma Aldrich

Synonym(S): VEGF112, Vasculotropin

Select a Size

Pack Size SKU Availability Price
5 μG V3388-5-μG In Stock ₹ 72,062.03

V3388 - 5 μG

₹ 72,062.03

In Stock

Quantity

1

Base Price: ₹ 72,062.03

GST (18%): ₹ 12,971.165

Total Price: ₹ 85,033.195

biological source

human

Quality Level

100

recombinant

expressed in E. coli

Assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

0.75-3.75 ng/mL ED50

mol wt

predicted mol wt ~28 kDa

packaging

pkg of 5 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

<1 EU/μg

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Description

  • Application: Vascular Endothelial Growth Factor (aa 207-318) human also known as VEGF 121 was used for preparing a cellular matrix hybridized with hyaluronic acid (ACM-HA) VEGF constructs which is used in measuring the VEGF-enhanced tissue-engineered bladder graft neovascularization by using dynamic contrast-enhanced MRI.[1] The product was used for creating VEGF-impregnated tissue-engineered construct which was inserted in the critical-sized calvarial defect in the membranous parietal bone of the rabbit for examining and characterizing the angiogenesis necessary for bone formation.[2]
  • Biochem/physiol Actions: Vascular Endothelial Growth Factor (aa 207-318) human also referred to as VEGF 121 or Vasculotropin is a basic protein that induces endothelial cell growth, vasculogenesis and angiogenesis. VEGF also enhances the growth of endothelial cells isolated from cerebral cortex, fetal and adult aorta as well as human umbilical vein.[3] Cells enhance VEGF 121 secretion from fibrin implants results in local and controlled blood vessel growth.[4]
  • Other Notes: 112 amino acid residue variant of human VEGF.
  • Physical form: Lyophilized from a 0.2 μm filtered solution in 30% acetronitrile and 0.1% TFA containing 0.25 mg bovine serum albumin.
  • Analysis Note: The biological activity is measured by its ability to stimulate 3H-thymidine incorporation in human umbilical vein endothelial cells.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Quality Level:
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recombinant:
expressed in E. coli

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≥97% (SDS-PAGE)

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lyophilized powder

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0.75-3.75 ng/mL ED50

mol wt:
predicted mol wt ~28 kDa

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pkg of 5 μg

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avoid repeated freeze/thaw cycles

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<1 EU/μg

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