S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt
≥80% (HPLC), ≥80% (spectrophotometric assay)
Manufacturer: Sigma Aldrich
CAS Number: 52248-03-0
Synonym(S): AdoMet, SAM p-toluenesulfonate salt
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 MG | A2408-25-MG | In Stock | ₹ 10,164.68 |
| 100 MG | A2408-100-MG | In Stock | ₹ 19,701.50 |
| 500 MG | A2408-500-MG | In Stock | ₹ 64,863.40 |
A2408 - 25 MG
In Stock
Quantity
1
Base Price: ₹ 10,164.68
GST (18%): ₹ 1,829.642
Total Price: ₹ 11,994.322
biological source
synthetic (Organic)
Quality Level
300
Assay
≥80% (HPLC)≥80% (spectrophotometric assay)
form
powder
composition
p-Toluenesulfonate content, 1.6-4.4 mol/mol
color
white to off-white
solubility
H2O: 100 mg/mL
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=C(O[H])[C@](N([H])[H])([H])C([H])([H])C([H])([H])[S@+](C([H])([H])[H])C([H])([H])[C@@]([C@](O[H])([H])[C@@]1([H])O[H])([H])O[C@]1([H])N2C3=C(N=C2[H])C(N([H])[H])=NC([H])=N3.O=S(C4=C([H])C([H])=C(C([H])([H])[H])C([H])=C4[H])([O-])=O
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Description
- General description: S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt is used for the treatment of depression, liver cirrhosis, cholestasis and degenerative joint disease.[1]
- Application: S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt has been used for cell proliferation assay.[2] It has also been used for methylation assay.[3][4]
- Biochem/physiol Actions: Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
- Caution: This material is unstable at room temperature.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
biological source: synthetic (Organic)
Quality Level: 300
Assay: ≥80% (HPLC)≥80% (spectrophotometric assay)
form: powder
composition: p-Toluenesulfonate content, 1.6-4.4 mol/mol
color: white to off-white
solubility: H2O: 100 mg/mL
shipped in: dry ice
storage temp.: −20°C
SMILES string: O=C(O[H])[C@](N([H])[H])([H])C([H])([H])C([H])([H])[S@+](C([H])([H])[H])C([H])([H])[C@@]([C@](O[H])([H])[C@@]1([H])O[H])([H])O[C@]1([H])N2C3=C(N=C2[H])C(N([H])[H])=NC([H])=N3.O=S(C4=C([H])C([H])=C(C([H])([H])[H])C([H])=C4[H])([O-])=O
biological source: Streptomyces sp.
Quality Level: 300
Assay: ~80% (HPLC)
form: solid
composition: __
color: yellow to yellow-orange
solubility: H2O: slightly soluble
shipped in: __
storage temp.: __
SMILES string: __
biological source: __
Quality Level: __
Assay: __
form: __
composition: __
color: __
solubility: __
shipped in: __
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SMILES string: __