G3381
Geldanamycin from Streptomyces hygroscopicus
≥98% (HPLC), powder
Manufacturer: Sigma Aldrich
CAS Number: 30562-34-6
Synonym(S): NSC 122750
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | G3381-1-MG | In Stock | ₹ 73,425.98 |
G3381 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 73,425.98
GST (18%): ₹ 13,216.676
Total Price: ₹ 86,642.656
sterility
non-sterile
Quality Level
300
Assay
≥98% (HPLC)
form
powder
color
yellow to orange
solubility
DMSO: soluble
antibiotic activity spectrum
neoplastics
Mode of action
enzyme | inhibits
storage temp.
−20°C
SMILES string
CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)\C(C)=C\C=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | TOKU-E Geldanamycin ReadyMade™ Solution, 30562-34-6, 10x1ML | TOKU-E | ₹ 17,026.44 | |
 | Sigma Aldrich Fine Chemicals Biosciences Geldanamycin Ready Made Solution 1 mg/mL, from Streptomyces hygroscopicus | 30562-34-6 | 1ml | Sigma Aldrich Fine Chemicals Biosciences | ₹ 23,582.90 | |
 | Tocris Bioscience™ Geldanamycin | Tocris Bioscience™ | ₹ 46,448.81 | |
 | Geldanamycin Ready Made Solution | Sigma Aldrich | ₹ 16,705.50 | |
| | Geldanamycin Ready Made Solution | Sigma Aldrich | ₹ 16,705.50 | |
 | [8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-9-[(Aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione | Aaron Chemicals LLC | ₹ 2,823.48 - ₹ 36,876.36 |
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Description
- General description: Chemical structure: benzenoid
- Biochem/physiol Actions: Geldanamycin is a potent antitumor antibiotic active at nanomolar concentration against 60 cell lines.Geldanamycin binds specifically to the heat shock protein Hsp90 and to its endoplasmic reticulum homologue GP96, and thus interferes with conformational maturation of proteins and the cellular stress response. In addition, Geldanamycin is a potent inhibitor of the nuclear hormone receptor family.
- Features and Benefits: This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
sterility: non-sterile
Quality Level: 300
Assay: ≥98% (HPLC)
form: powder
color: yellow to orange
solubility: DMSO: soluble
antibiotic activity spectrum: neoplastics
Mode of action: enzyme | inhibits
storage temp.: −20°C
SMILES string: CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)\C(C)=C\C=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O
sterility:
non-sterile
Quality Level:
300
Assay:
≥98% (HPLC)
form:
powder
color:
yellow to orange
solubility:
DMSO: soluble
antibiotic activity spectrum:
neoplastics
Mode of action:
enzyme | inhibits
storage temp.:
−20°C
SMILES string:
CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)\C(C)=C\C=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O
sterility: __
Quality Level: 200
Assay: 99%
form: __
color: __
solubility: water: soluble 5 mg/mL, clear to slightly hazy, colorless to faintly yellowalcohol: soluble(lit.)chloroform: soluble(lit.)
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: OC(=O)CCCC(O)=O
sterility:
__
Quality Level:
200
Assay:
99%
form:
__
color:
__
solubility:
water: soluble 5 mg/mL, clear to slightly hazy, colorless to faintly yellowalcohol: soluble(lit.)chloroform: soluble(lit.)
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
__
SMILES string:
OC(=O)CCCC(O)=O
sterility: __
Quality Level: 200
Assay: ≥98% (TLC)
form: powder
color: white
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
SMILES string: NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
sterility:
__
Quality Level:
200
Assay:
≥98% (TLC)
form:
powder
color:
white
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
SMILES string:
NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
sterility: __
Quality Level: 200
Assay: ≥98% (TLC)
form: powder
color: white
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
SMILES string: NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
sterility:
__
Quality Level:
200
Assay:
≥98% (TLC)
form:
powder
color:
white
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
SMILES string:
NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O