L2515

Lipoteichoic acid from Staphylococcus aureus

bacterial cell wall polymer

Manufacturer: Sigma Aldrich

CAS Number: 56411-57-5

Select a Size

Pack Size SKU Availability Price
5 MG L2515-5-MG In Stock ₹ 19,355.10
10 MG L2515-10-MG In Stock ₹ 34,445.15
25 MG L2515-25-MG In Stock ₹ 53,042.50

L2515 - 5 MG

₹ 19,355.10

In Stock

Quantity

1

Base Price: ₹ 19,355.10

GST (18%): ₹ 3,483.918

Total Price: ₹ 22,839.018

biological source

Staphylococcus aureus

Quality Level

200

form

lyophilized powder

functional group

phospholipid

lipid type

polymerizable lipids

shipped in

ambient

storage temp.

2-8°C

Related Products

Img

Sigma Aldrich

L3265

--

Img

Sigma Aldrich

L6136

purified by phenol extraction...

Img

Sigma Aldrich

L2012

purified by gel-filtration chromato...

Img

Sigma Aldrich

D6001

average mol wt >500,000 (dextran st...

Img

Sigma Aldrich

D8787

avg mol wt >500,000 (dextran starti...

Img

Sigma Aldrich

52423

low sulfate content, Mr ~40,000...

Img

Sigma Aldrich

C6719

--

Img

Sigma Aldrich

SMB00288

≤1.00 EU/mg Endotoxin...

Description

  • General description: Lipoteichoic acid (LTA) is a linear polymer of phosphodiester-linked glycerol phosphate covalently bound to a lipid. The C2 position on the glycerol-phosphate is usually glycosylated or D-alanylated. LTA is amphipathic due to the presence of the negatively charged backbone of glycerol phosphate and the hydrophobic lipid. The lipid portion is bound hydrophobically to the cell membrane, whereas the polyglycerol phosphate portion extends into the cell wall.
  • Application: Lipoteichoic acid from Staphylococcus aureus has been used:to investigate the binding properties of SpHyastatin to lipopolysaccharides and lipoteichoic acid using enzyme-linked immunosorbent assay (ELISA)to measure the interleukin (IL-6) produced in splenocytes using a sandwich ELISAas a toll-like receptor 2/6 (TLR2/6) agonist to explore its potential to induce tumoricidal M1 macrophage phenotype
  • Biochem/physiol Actions: Lipoteichoic acid (LTA) is a complex component of cell walls of Gram-positive bacteria that are involved in a wide range of cell processes such as the stimulation of immune responses and cell signaling pathways. LTA differs between species of gram-positive bacteria. Lipoteichoic acid from Streptococcus aureus may be used to compare its structure, immunogenicity and functions versus other bacterial LTAs.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves