P5396

Phosphomycin disodium salt

antibacterial MurA inhibitor

Manufacturer: Sigma Aldrich

Synonym(S): (−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, Fosfomycin, Phosphonomycin

Select a Size

Pack Size SKU Availability Price
1 G P5396-1-G In Stock ₹ 4,838.78
5 G P5396-5-G In Stock ₹ 12,773.50
50 G P5396-50-G In Stock ₹ 52,068.25

P5396 - 1 G

₹ 4,838.78

In Stock

Quantity

1

Base Price: ₹ 4,838.78

GST (18%): ₹ 870.98

Total Price: ₹ 5,709.76

Quality Level

200

form

powder

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteria

Mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[Na+].[Na+].C[C@@H]1O[C@@H]1P([O-])([O-])=O

InChI

1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1

InChI key

QZIQJIKUVJMTDG-JSTPYPERSA-L

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Description

  • Application: Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections. It is used for susceptibility studies of Klebsiella pneumoniae[1] and to study in vitro susceptibility testing procedures for fosfomycin tromethamine[2].
  • Biochem/physiol Actions: Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.
  • Other Notes: 1g,5g,50g

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Show Difference

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Sigma Aldrich

P5396

antibacterial MurA inhibitor...


Quality Level:
200

form:
powder

antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteria

Mode of action:
cell wall synthesis | interferes

storage temp.:
2-8°C

SMILES string:
[Na+].[Na+].C[C@@H]1O[C@@H]1P([O-])([O-])=O

InChI:
1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1

InChI key:
QZIQJIKUVJMTDG-JSTPYPERSA-L

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[Li].[P](=O)(O[P](=O)(OCC([C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC)(C)C)O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O[P](=O)(O)O)O)[n]2c3ncnc(c3nc2)N)O

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InChI:
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InChI key:
__