T6069

Thio-TEPA

Manufacturer: Sigma Aldrich

CAS Number: 52-24-4

Synonym(S): N,N′,N″-Triethylenethiophosphoramide, Thio-Tep, Thiofozil, Thiotef, Tio-tef, Tiofosfamid, Tiofosyl, Tiofozil, Tris(aziridinyl)phosphine sulfide

Select a Size

Pack Size SKU Availability Price
1 G T6069-1-G In Stock ₹ 30,927.03

T6069 - 1 G

₹ 30,927.03

In Stock

Quantity

1

Base Price: ₹ 30,927.03

GST (18%): ₹ 5,566.865

Total Price: ₹ 36,493.895

form

solid

Quality Level

200

storage condition

(Keep container tightly closed in a dry and well-ventilated place.)

color

white

antibiotic activity spectrum

neoplastics

Mode of action

DNA synthesis | interferes

storage temp.

2-8°C

SMILES string

S=P(N1CC1)(N2CC2)N3CC3

InChI

1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2

InChI key

FOCVUCIESVLUNU-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
1664000
Thiotepa
Sigma Aldrich ₹ 37,227.18
BP331
Thiotepa
Sigma Aldrich ₹ 23,750.05

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Description

  • General description: Chemical structure: aziridine
  • Application: A polyfunctional alkylating agent
  • Biochem/physiol Actions: The unstable nitrogen-carbon groups alkylate with DNA which causes irreversible DNA damage. They stop tumor growth by crosslinking guanine nucleobases in DNA double-helix strands, directly attacking DNA. The DNA strands are unable to uncoil and separate which halts cell division[1].
  • Analysis Note: Solubility - freely soluble in water , in chloroform and in ethanol (96%)
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

Pictograms

GHS06,GHS08

Signal Word

Danger

Hazard Statements

H300,H350

Precautionary Statements

P202 - P264 - P280 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 2 Oral - Carc. 1B

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T6069

--


form:
solid

Quality Level:
200

storage condition:
(Keep container tightly closed in a dry and well-ventilated place.)

color:
white

antibiotic activity spectrum:
neoplastics

Mode of action:
DNA synthesis | interferes

storage temp.:
2-8°C

SMILES string:
S=P(N1CC1)(N2CC2)N3CC3

InChI:
1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2

InChI key:
FOCVUCIESVLUNU-UHFFFAOYSA-N

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Mode of action:
protein synthesis | interferes

storage temp.:
2-8°C

SMILES string:
O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC

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__

InChI key:
__

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SMILES string:
FC(F)(F)C(=O)O[Ag]

InChI:
1S/C2HF3O2.Ag/c3-2(4,5)1(6)7;/h(H,6,7);/q;+1/p-1

InChI key:
KZJPVUDYAMEDRM-UHFFFAOYSA-M