V0627

Valinomycin

≥98% (TLC), ≥90% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 2001-95-8

Synonym(S): Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid

Select a Size

Pack Size SKU Availability Price
10 MG V0627-10-MG In Stock ₹ 10,543.55
25 MG V0627-25-MG In Stock ₹ 18,554.05
100 MG V0627-100-MG In Stock ₹ 47,218.65
500 MG V0627-500-MG In Stock ₹ 2,22,302.20

V0627 - 10 MG

₹ 10,543.55

In Stock

Quantity

1

Base Price: ₹ 10,543.55

GST (18%): ₹ 1,897.839

Total Price: ₹ 12,441.389

Quality Level

300

Assay

≥90% (HPLC)≥98% (TLC)

form

powder

storage condition

(Keep container tightly closed in a dry and well-ventilated place.)

color

white

solubility

DMSO: ≥50 mg/mLH2O: insoluble

antibiotic activity spectrum

Gram-positive bacteriaparasitesviruses

Mode of action

cell membrane | interferes

storage temp.

2-8°C

SMILES string

CC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)[C@@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C

Other Options

Image Product Name Manufacturer Price Range
60403
Potassium ionophore I
Supelco ₹ 64,148.95
94675
Valinomycin
Sigma Aldrich ₹ 11,322.95 - ₹ 1,86,114.23
V3639
Valinomycin
Sigma Aldrich ₹ 9,948.18

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Description

  • General description: Chemical structure: peptide
  • Application: Valinomycin has been used: to equilibrate intracellular pH and extracellular pH of 5 (and 6-)-carboxyfluorescein succinimidyl ester (cFSE) in Escherichia coli strain B23[3]as an ionophore to equilibrate intracellular pH and extracellular pH of lactic acid bacteria (LAB) strains[4]to establish the desired pH for acid-base transition and formation of K+-valinomycin diffusion potential[5]
  • Biochem/physiol Actions: K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction.
  • Packaging: 10MG,25MG,100MG,500MG
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H300 + H310

Precautionary Statements

P262 - P264 - P280 - P301 + P310 - P302 + P352 + P310 - P361 + P364

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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CC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)[C@@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C

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SMILES string:
O.CC(O)=O.NC(=N)NCCC[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]2CSSCCC(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N2)C(=O)NCC(N)=O