Biotin-SLF
Manufacturer: Sigma Aldrich
CAS Number: 2230857-85-7
Synonym(S): (R)-3-(3,4-Dimethoxyphenyl)-1-(3-(4,18-dioxo-22-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-8,11,14-trioxa-5,17-diazadocosanamido)phenyl)propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate, Bio-SLF, Biotin-conjugated FKBP12WT-directed ligand, Biotin-conjugated SLF ligand, FKBP12WT affinity probe for PROTAC® and targeted protein degradation research
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 914223-5-MG | In Stock | ₹ 64,181.43 |
914223 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 64,181.43
GST (18%): ₹ 11,552.657
Total Price: ₹ 75,734.087
ligand
biotin
Quality Level
100
form
powder
storage temp.
−20°C
SMILES string
O=C(CCC(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O)=O)NC3=CC([C@H](OC([C@@H]4CCCCN4C(C(C(C)(C)CC)=O)=O)=O)CCC5=CC=C(OC)C(OC)=C5)=CC=C3
Related Products
Description
- Application: Biotin-SLF (bio-SLF) is an FKBP12WT affinity probe useful in chemical biology or targeted protein degradation where FKBP12 is used as a tool protein and its enrichment is required in discovery experiments or assay validation.Related tools:Additional bifunctional tools for FKPB12 variants: dTAG-13 (SML2601) for FKBP12F36V; and KB02-SLF (914738), KB03-SLF (914975), and KB04-SLF (913715) for FKBP12WTCereblon (CRBN) affinity probe: Biotin-Thalidomide (913979)Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)
- Other Notes: The dTAG system for immediate and target-specific protein degradationTechnology Spotlight: Building PROTAC® Degraders for Targeted Protein Degradation
- Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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ligand: biotin
Quality Level: 100
form: powder
storage temp.: −20°C
SMILES string: O=C(CCC(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O)=O)NC3=CC([C@H](OC([C@@H]4CCCCN4C(C(C(C)(C)CC)=O)=O)=O)CCC5=CC=C(OC)C(OC)=C5)=CC=C3
ligand: __
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SMILES string: __
ligand: __
Quality Level: 100
form: liquid
storage temp.: __
SMILES string: __