65-875

Tocris Bioscience™ TAK 242

Manufacturer: Tocris Bioscience™

CAS Number: 243984-11-4

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Pack Size SKU Availability Price
Each of 1 65-875-Each-of-1 In Stock ₹ 25,368.54

65-875 - Each of 1

₹ 25,368.54

In Stock

Quantity

1

Base Price: ₹ 25,368.54

GST (18%): ₹ 4,566.337

Total Price: ₹ 29,934.877

Chemical Name or Material

(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate

Quantity

5 mg

Formula Weight

361.82

CAS

243984-11-4

Molecular Formula

C15H17ClFNO4S

Purity

98%

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Description

  • TAK 242 is a toll-like receptor 4 (TLR4) signaling inhibitor
  • Binds to intracellular domain of TLR4
  • Inhibits LPS-induced cytokine production in vitro (IC50 values are 1.3, 1.3 and 3.2 nM for IL-6, TNFα and NO production)
  • Reduces lesion volume in a mouse model of cerebral cavernous malformations (CCMs)
  • Also attenuates increased cytokine levels in a mouse sepsis model, when given in combination with ceftazidime
  • Cell permeable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

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Tocris Bioscience™

65-875

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Chemical Name or Material:
(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate

Quantity:
5 mg

Formula Weight:
361.82

CAS:
243984-11-4

Molecular Formula:
C15H17ClFNO4S

Purity:
98%

Img

Tocris Bioscience™

65-892-5

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Chemical Name or Material:
(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-N-2-propyn-1-yl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide

Quantity:
25 mg

Formula Weight:
437.95

CAS:
2115701-93-2

Molecular Formula:
C22H20ClN5OS

Purity:
95%

Img

Tocris Bioscience™

65-902

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Chemical Name or Material:
2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-4-((2-(2,5-dioxo-2,5-dihydro-1 H-pyrrol-1-yl)ethyl)carbamoyl)benzoate

Quantity:
2 mg

Formula Weight:
618.75

CAS:
__

Molecular Formula:
C35H34N4O5Si

Purity:
95%

Img

Tocris™

65-981-0

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Chemical Name or Material:
6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine hydrochloride

Quantity:
10 mg

Formula Weight:
367.23

CAS:
1638644-62-8

Molecular Formula:
C16H15ClN4O2.HCl

Purity:
98%