69-235-0

Tocris Bioscience™ AMZ 30

Manufacturer: Fischer Scientific

CAS Number: 1313613-09-0

Select a Size

Pack Size SKU Availability Price
Each of 1 69-235-0-Each-of-1 In Stock ₹ 63,519.74

69-235-0 - Each of 1

₹ 63,519.74

In Stock

Quantity

1

Base Price: ₹ 63,519.74

GST (18%): ₹ 11,433.553

Total Price: ₹ 74,953.293

Chemical Name or Material

(2 E)-2-[(4-Fluorophenyl)sulfonyl]-3-[1-[(3-nitrophenyl)sulfonyl]-1 H-pyrrol-2-yl]-2-propenenitrile

Quantity

50 mg

Molecular Formula

C19H12FN3O6S2

CAS

1313613-09-0

Target

Hydrolase Inhibitors

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
7250164
Tocris Bioscience™ AMZ 30
Fischer Scientific --
69-231-0
Tocris Bioscience™ AMZ 30
Fischer Scientific ₹ 15,085.94
50-243-3344
eMolecules​ Ambeed / (E)-2-((4-Fluorophenyl)sulfonyl)-3-(1-((3-nitrophenyl)sulfonyl)-1H-pyrrol-2-yl)acrylonitrile / 1mg / 761012790 / A781030 / / 1313613-09-0 / MFCD28900741 / 461.440 / C19H12FN3O6S2
eMolecules​ ₹ 3,205.08
AE35862
1313613-09-0 | AMZ30
A2B Chem ₹ 2,053.44 - ₹ 6,417.00

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Description

  • AMZ 30 is a potent, selective and irreversible inhibitor of protein phosphatase methylesterase-1 (PME-1; IC50 = 600 nM) with > 100-fold selectivity for PME-1 over other serine hydrolases in human cell lysates
  • AMZ 30 inactivates PME-1 and reduces the demethylated form of serine/threonine protein phosphatase 2A (PP2A) in HEK 293T cells
  • AMZ 30 perturbs leucine carboxyl methyltransferase-1 (LCMT1)-PME-1 methylation equilibrium leading to shortening of mitotic spindles and mitotic arrest in HeLa cells
  • It also shows antiproliferative properties in an in vitro model of endometrial carcinoma.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

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Fischer Scientific

69-235-0

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Chemical Name or Material:
(2 E)-2-[(4-Fluorophenyl)sulfonyl]-3-[1-[(3-nitrophenyl)sulfonyl]-1 H-pyrrol-2-yl]-2-propenenitrile

Quantity:
50 mg

Molecular Formula:
C19H12FN3O6S2

CAS:
1313613-09-0

Target:
Hydrolase Inhibitors

Purity:
0.98

Img

MilliporeSigma™

69-237-3

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Chemical Name or Material:
__

Quantity:
100 μg

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__

Img

MilliporeSigma™

69-238-3

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Chemical Name or Material:
__

Quantity:
100 μg

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__

Img

MilliporeSigma™

69-239-3

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Chemical Name or Material:
__

Quantity:
100 μg

Molecular Formula:
__

CAS:
__

Target:
__

Purity:
__