7110878
Tocris Bioscience™ VU 0409551
Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable
Manufacturer: Fischer Scientific
CAS Number: 1363281-27-9
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Chemical Name or Material
[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone
Synonym
JNJ 46778212
Molecular Formula
C20H17FN2O3
Purity
>98%
CAS
1363281-27-9
Target
Group I mGluR Modulators
Formula Weight
352.36
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ VU 0409551 | Fischer Scientific | ₹ 1,10,115.72 | |
| | Tocris Bioscience™ VU 0409551 | Fischer Scientific | ₹ 26,395.26 | |
 | eMolecules Medchem Express / JNJ-46778212 / 5mg / 415688241 / HY-19559 / / 1363281-27-9 / MFCD29047143 / 352.365 / C20H17FN2O3 | eMolecules | ₹ 8,816.10 | |
 | Medchemexpress LLC HY-19559 5mg Medchemexpress, JNJ-46778212 CAS:1363281-27-9 Purity:>98% | Medchemexpress LLC | ₹ 6,288.66 | |
 | 1363281-27-9 | 5-(4-fluorobenzoyl)-2-(phenoxymethyl)-4H,5H,6H,7H-[1,3]oxazolo[5,4-c]pyridine | A2B Chem | ₹ 2,481.24 - ₹ 64,255.56 |
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Description
- Selective mGlu5 positive allosteric modulator (EC50 = 260 nM)
- Selective for mGlu5 over other mGluR subtypes, as well as 66 other receptors and ion channels
- Selectively potentiates mGlu5 signaling via Gαq
- Exhibits wake-promoting, antipsychotic-like and cognition-enhancing effects in animal models
- Brain penetrant and orally available.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C
Compare Similar Items
Show Difference
Chemical Name or Material: [6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone
Synonym: JNJ 46778212
Molecular Formula: C20H17FN2O3
Purity: >98%
CAS: 1363281-27-9
Target: Group I mGluR Modulators
Formula Weight: 352.36
Chemical Name or Material:
[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone
Synonym:
JNJ 46778212
Molecular Formula:
C20H17FN2O3
Purity:
>98%
CAS:
1363281-27-9
Target:
Group I mGluR Modulators
Formula Weight:
352.36
Chemical Name or Material: 6-[4-[(2-Methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one
Synonym: __
Molecular Formula: C23H22N2O4
Purity: >98%
CAS: 500164-74-9
Target: NFkB/IkB Inhibitors
Formula Weight: 390.43
Chemical Name or Material:
6-[4-[(2-Methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one
Synonym:
__
Molecular Formula:
C23H22N2O4
Purity:
>98%
CAS:
500164-74-9
Target:
NFkB/IkB Inhibitors
Formula Weight:
390.43
Chemical Name or Material: (1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride
Synonym: __
Molecular Formula: C16H15F2NO.HCl
Purity: >98%
CAS: 1239262-36-2
Target: Histone Demethylase Inhibitors
Formula Weight: 311.75
Chemical Name or Material:
(1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride
Synonym:
__
Molecular Formula:
C16H15F2NO.HCl
Purity:
>98%
CAS:
1239262-36-2
Target:
Histone Demethylase Inhibitors
Formula Weight:
311.75
Chemical Name or Material: 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol
Synonym: __
Molecular Formula: C17H17N5O
Purity: >98%
CAS: 1309198-71-7
Target: Orphan 7-TM Receptor Agonists
Formula Weight: 307.35
Chemical Name or Material:
2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol
Synonym:
__
Molecular Formula:
C17H17N5O
Purity:
>98%
CAS:
1309198-71-7
Target:
Orphan 7-TM Receptor Agonists
Formula Weight:
307.35