7110904
Tocris Bioscience™ Akti-1/2
Potent and selective dual Akt1 and 2 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 612847-09-3
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Chemical Name or Material
1,3-Dihydro-1-[1-[[4-(6-phenyl-1 H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2 H-benzimidazol-2-one
Synonym
Akt Inhibitor VIII
Molecular Formula
C34H29N7O
Purity
98%
CAS
612847-09-3
Target
Akt (Protein Kinase B) Inhibitors
Formula Weight
551.64
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ Akti-1/2 | Fischer Scientific | ₹ 90,779.16 | |
| | Tocris Bioscience™ Akti-1/2 | Fischer Scientific | ₹ 22,288.38 | |
 | Enzo Life Sciences Akt inhibitor VIII (1mg). CAS: 612847-09-3 | Enzo Life Sciences | ₹ 12,889.61 | |
| | Enzo Life Sciences Akt inhibitor VIII (5mg). CAS: 612847-09-3 | Enzo Life Sciences | ₹ 21,745.07 | |
 | 612847-09-3 | AKTI-1/2 | A2B Chem | ₹ 4,278.00 - ₹ 87,356.76 |
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Description
- Potent and selective dual Akt1 and 2 inhibitor (IC50 values are 50 and 210 nM, respectively)
- Selective for Akt1 and 2 over a panel of other tyrosine and serine/threonine kinases
- Sensitizes LnCaP cells to TRAIL (TNF-related apoptosis-inducing ligand) induced apoptosis
- Also enhances CAR and TCR retroviral transduction of human T cells
- Active in vivo .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: 1,3-Dihydro-1-[1-[[4-(6-phenyl-1 H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2 H-benzimidazol-2-one
Synonym: Akt Inhibitor VIII
Molecular Formula: C34H29N7O
Purity: 98%
CAS: 612847-09-3
Target: Akt (Protein Kinase B) Inhibitors
Formula Weight: 551.64
Chemical Name or Material:
1,3-Dihydro-1-[1-[[4-(6-phenyl-1 H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2 H-benzimidazol-2-one
Synonym:
Akt Inhibitor VIII
Molecular Formula:
C34H29N7O
Purity:
98%
CAS:
612847-09-3
Target:
Akt (Protein Kinase B) Inhibitors
Formula Weight:
551.64
Chemical Name or Material: N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide
Synonym: __
Molecular Formula: C26H28N4O3
Purity: >98%
CAS: 181223-80-3
Target: ERK Inhibitors
Formula Weight: 444.53
Chemical Name or Material:
N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide
Synonym:
__
Molecular Formula:
C26H28N4O3
Purity:
>98%
CAS:
181223-80-3
Target:
ERK Inhibitors
Formula Weight:
444.53
Chemical Name or Material: rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one
Synonym: __
Molecular Formula: C25H28N6O
Purity: >98%
CAS: 1645286-75-4
Target: Tankyrase Inhibitors
Formula Weight: 428.53
Chemical Name or Material:
rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one
Synonym:
__
Molecular Formula:
C25H28N6O
Purity:
>98%
CAS:
1645286-75-4
Target:
Tankyrase Inhibitors
Formula Weight:
428.53
Chemical Name or Material: N-5-Isoquinolinyl-N′-[[(4-(trifluoromethyl)phenyl]methyl]urea
Synonym: __
Molecular Formula: C18H14F3N3O
Purity: >98%
CAS: 581809-67-8
Target: TRPV Antagonists
Formula Weight: 345.32
Chemical Name or Material:
N-5-Isoquinolinyl-N′-[[(4-(trifluoromethyl)phenyl]methyl]urea
Synonym:
__
Molecular Formula:
C18H14F3N3O
Purity:
>98%
CAS:
581809-67-8
Target:
TRPV Antagonists
Formula Weight:
345.32