7166811
Tocris™ BQCA
Positive allosteric modulator of M1 receptors
Manufacturer: Fischer Scientific
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Molecular Formula
C18H15NO4
Formula Weight
309.32
Product Type
Positive Allosteric Modulator
Purity
98%
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Description
- BQCA is a muscarinic M1 receptor positive allosteric modulator (pKB 5.76 - 5.82)
- Exhibits selectivity for M1 over M3 and M5 receptors
- Enhances ACh effects at M1 receptors in an IP1- accumulation assay, without affecting ACh binding
- Increases markers of neuronal activation in brains of wild-type but not M1-/- mice in vivo
- Prevents Scopolamine (Cat
- No
- 1414)-induced memory deficits in mice in a contextual fear conditioning model.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Molecular Formula: C18H15NO4
Formula Weight: 309.32
Product Type: Positive Allosteric Modulator
Purity: 98%
Molecular Formula:
C18H15NO4
Formula Weight:
309.32
Product Type:
Positive Allosteric Modulator
Purity:
98%
Molecular Formula: C15H14Cl2N2O3S
Formula Weight: 373.25
Product Type: Activator
Purity: 98%
Molecular Formula:
C15H14Cl2N2O3S
Formula Weight:
373.25
Product Type:
Activator
Purity:
98%
Molecular Formula: C25H26F3N5O3
Formula Weight: 501.51
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C25H26F3N5O3
Formula Weight:
501.51
Product Type:
Inhibitor
Purity:
98%
Molecular Formula: C19H14N2O7S
Formula Weight: 414.39
Product Type: Inhibitor
Purity: 98%
Molecular Formula:
C19H14N2O7S
Formula Weight:
414.39
Product Type:
Inhibitor
Purity:
98%