7235753

Tocris™ Conduritol B epoxide

Irreversible glucocerebrosidase (β-glucosidase) inhibitor; used to generate Gaucher disease models

Manufacturer: Fischer Scientific

CAS Number: 6090-95-5

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Chemical Name or Material

DL-1,2-Anhydro-myo-Inositol

CAS

6090-95-5

Target

Glycosylase Inhibitors

Molecular Formula

C6H10O5

Other Options

Image Product Name Manufacturer Price Range
70-562-5
Tocris™ Conduritol B epoxide
Fischer Scientific ₹ 48,426.96
70-565
Tocris™ Conduritol B epoxide
Fischer Scientific ₹ 12,235.08
50-201-1732
Enzo Life Sciences Conduritol B Epoxide (25 mg). CAS: 6090-95-5
Enzo Life Sciences ₹ 30,600.53
50-213-8005
eMolecules​ Conduritol B Epoxide | 6090-95-5 | | 250mg
eMolecules​ ₹ 39,972.78
C5424
Conduritol B epoxide
Sigma Aldrich ₹ 17,471.55 - ₹ 62,308.70
CS-6107
Conduritol B epoxide
ChemScene ₹ 16,256.40 - ₹ 74,009.40

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Description

  • Conduritol B epoxide is an irreversible glucocerebrosidase (GBA) inhibitor (Ki = 53 μM; IC50 = 4.28 - 9.49 μM)
  • Also inhibitis lysosomal α-glucosidase
  • Used to generate animal models of Gaucher disease
  • Accelerates recovery of peripheral nerve injury in mice
  • Preserves motoneurons and ganglioside distribution at the neuromuscular junction, delays disease onset and improves motor function in a mouse ALS model.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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