7249497
Tocris Bioscience™ AZD 7648
Potent and selective DNA-PK inhibitor
Manufacturer: Fischer Scientific
CAS Number: 2230820-11-6
The price for this product is unavailable. Please request a quote
Chemical Name or Material
7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one
CAS
2230820-11-6
Target
DNA-dependent Protein Kinase Inhibitors
Molecular Formula
C18H20N8O2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ AZD 7648 | Fischer Scientific | ₹ 18,780.42 | |
| | Tocris Bioscience™ AZD 7648 | Fischer Scientific | ₹ 79,100.22 | |
 | Medchemexpress LLC HY-111783 250mg , AZD-7648 CAS:2230820-11-6 Purity:>98% | Medchemexpress LLC | ₹ 94,329.90 | |
| | Medchemexpress LLC HY-111783 25mg , AZD-7648 CAS:2230820-11-6 Purity:>98% | Medchemexpress LLC | ₹ 22,459.50 | |
| | eMolecules Ambeed / 7-Methyl-2-((7-methyl-[124]triazolo[15-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7H-purin-8(9H)-one / 1mg / 682927853 / A1175994 / / 2230820-11-6 / [null] / 380.412 / C18H20N8O2 | eMolecules | ₹ 3,730.42 | |
 | Medchemexpress LLC HY-111783 10mg Medchemexpress, AZD-7648 CAS:2230820-11-6 Purity:>98% | Medchemexpress LLC | ₹ 13,475.70 | |
 | 2230820-11-6 | 7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one | A2B Chem | ₹ 2,566.80 - ₹ 71,870.40 |
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Description
- AZD 7648 is a potent (IC50 = 0.6 nM in an enzyme assay) and selective DNA-PK inhibitor
- It is selective for DNA-PK over a range of kinases including PI3Kα, PI3Kδ, PI3Kγ, ATM, ATR and mTOR
- In combination with radiotherapy, it leads to tumor regression in fully immuno-competent mice models
- It also enhances the activity of PARP inhibitor Olaparib (Cat
- No
- 7579)
- AZD 7648 is orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
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Chemical Name or Material: 7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one
CAS: 2230820-11-6
Target: DNA-dependent Protein Kinase Inhibitors
Molecular Formula: C18H20N8O2
Chemical Name or Material:
7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one
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Molecular Formula:
C18H20N8O2
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