78-251-0

Tocris Bioscience™ AZD 7648

Manufacturer: Fischer Scientific

CAS Number: 2230820-11-6

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Pack Size SKU Availability Price
Each of 1 78-251-0-Each-of-1 In Stock ₹ 18,780.42

78-251-0 - Each of 1

₹ 18,780.42

In Stock

Quantity

1

Base Price: ₹ 18,780.42

GST (18%): ₹ 3,380.476

Total Price: ₹ 22,160.896

Chemical Name or Material

7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one

Quantity

10 mg

Molecular Formula

C18H20N8O2

CAS

2230820-11-6

Target

DNA-dependent Protein Kinase Inhibitors

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Description

  • AZD 7648 is a potent (IC50 = 0.6 nM in an enzyme assay) and selective DNA-PK inhibitor
  • It is selective for DNA-PK over a range of kinases including PI3Kα, PI3Kδ, PI3Kγ, ATM, ATR and mTOR
  • In combination with radiotherapy, it leads to tumor regression in fully immuno-competent mice models
  • It also enhances the activity of PARP inhibitor Olaparib (Cat
  • No
  • 7579)
  • AZD 7648 is orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Compare Similar Items

Show Difference

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Fischer Scientific

78-251-0

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Chemical Name or Material:
7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one

Quantity:
10 mg

Molecular Formula:
C18H20N8O2

CAS:
2230820-11-6

Target:
DNA-dependent Protein Kinase Inhibitors

Img

Fischer Scientific

78-255-0

--


Chemical Name or Material:
7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one

Quantity:
50 mg

Molecular Formula:
C18H20N8O2

CAS:
2230820-11-6

Target:
DNA-dependent Protein Kinase Inhibitors

Img

Fischer Scientific

78-261-0

--


Chemical Name or Material:
rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide

Quantity:
10 mg

Molecular Formula:
C26H26F3N3O3

CAS:
956697-53-3

Target:
Smoothened

Img

Fischer Scientific

78-265-0

--


Chemical Name or Material:
rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide

Quantity:
50 mg

Molecular Formula:
C26H26F3N3O3

CAS:
956697-53-3

Target:
Smoothened