930563

Pomalidomide-PEG2-C2-azide

≥95%

Manufacturer: Sigma Aldrich

CAS Number: 2271036-45-2

Synonym(S): 1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-(2-Azidoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl), 4-[[2-[2-(2-Azidoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

Select a Size

Pack Size SKU Availability Price
50 MG 930563-50-MG In Stock ₹ 25,135.65

930563 - 50 MG

₹ 25,135.65

In Stock

Quantity

1

Base Price: ₹ 25,135.65

GST (18%): ₹ 4,524.417

Total Price: ₹ 29,660.067

ligand

pomalidomide

Quality Level

100

Assay

≥95%

form

powder

functional group

azide

storage temp.

2-8°C

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Description

  • Application: Pomalidomide-PEG2-C2-azide is a functionalized cereblon ligand for development of pomalidomide-based PROTACs. Contains an alkyne, allowing for conjugation through click chemistry. A basic building block for development of a protein degrader library. Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationProtein Degrader Building Blocks
  • Other Notes: Targeted Protein Degradation by Small MoleculesDestruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug DiscoveryImpact of linker length on the activity of PROTACs

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H360D

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

WGK

WGK 3

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