PI90102
Thermo Scientific™ iodoTMTsixplex™ Isobaric Label Reagents and Kits
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Pack of 1 | PI90102-Pack-of-1 | In Stock | ₹ 2,69,514.00 |
PI90102 - Pack of 1
In Stock
Quantity
1
Base Price: ₹ 2,69,514.00
GST (18%): ₹ 48,512.52
Total Price: ₹ 3,18,026.52
For Use With (Equipment)
Mass Spectrometer
Product Line
iodoTMTsixplex™
Label or Dye
Tandem Mass Tag™ (TMT) Labels
Final Product Type
Protein
Workflow Step
Protein Labeling
Product Type
Isobaric Label Reagent Set
Content And Storage
Sufficient for: Five sixplex (5 x 6-way) experiments• iodoTMT6-126 Label Reagent, 5 x 0.2 mg• iodoTMT6-127 Label Reagent, 5 x 0.2 mg• iodoTMT6-128 Label Reagent, 5 x 0.2 mg• iodoTMT6-129 Label Reagent, 5 x 0.2 mg• iodoTMT6-130 Label Reagent, 5 x 0.2 mg• iodoTMT6-131 Label Reagent, 5 x 0.2 mgStore at –20°C.
Starting Material
Cell Lysate
Detection Method
Mass Spectrometry
Quantity
5 x 0.2 mg (per tag)
Related Products
Description
- Thermo Scientific iodoTMT Label reagents enable multiplexed identification and quantitation of cysteine containing peptides in different samples using tandem mass spectrometry
- IodoTMT reagents are sets of isobaric (mass and structure) isomers that are iodoacetyl-activated for covalent, irreversible labeling of sulfhydryl (–SH) groups
- iodoTMTzero Label Reagent allows testing and optimization of sample preparation, labeling, fractionation, and MS fragmentation for peptide identification and reporter detection without using the more costly isotope-labeled compounds
- Iodoacetyl tandem mass tag reagents enable selective labeling of cysteine-containing peptides for multiplexed sample quantitation using LC-MS/MS analysis
- Similar to iodoacetamide, iodoTMT reagents react specifically with reduced cysteines (Cys) in peptides and proteins and enable quantitation of the relative abundance of cysteine modifications, such as S-nitrosylation and the oxidation of disulfide bonds
- IodoTMT reagents irreversibly label free sulfhydryl groups on cysteine residues, in contrast to previous reversible cysteine-reactive TMT (cysTMT) reagents
- To selectively analyze the cysteine-labeled peptides, the sample may be enriched using Immobilized Anti-TMT Antibody Resin (Cat
- No
- 90076) and TMT Elution Buffer (Cat
- No
- 90104)
- This approach of selective thiol-labeling and affinity enrichment is similar to isotope-coded affinity tags (ICAT method) but allows for affinity enrichment with a non-biological tag and higher multiplex quantitation
- Features of iodoTMT reagents • Specific —only reacts with sulfhydryl groups (reduced, unmodified cysteine residues) • Irreversible —labeled proteins and peptides are not susceptible to reducing agents • Flexible —options for duplex isotopic (MS) or sixplex isobaric (MS/MS) quantitation • Versatile —can be used to study cysteine modifications (e.g., di-sulfide bridges, S-nitrosylation)
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For Use With (Equipment): Mass Spectrometer
Product Line: iodoTMTsixplex™
Label or Dye: Tandem Mass Tag™ (TMT) Labels
Final Product Type: Protein
Workflow Step: Protein Labeling
Product Type: Isobaric Label Reagent Set
Content And Storage: Sufficient for: Five sixplex (5 x 6-way) experiments• iodoTMT6-126 Label Reagent, 5 x 0.2 mg• iodoTMT6-127 Label Reagent, 5 x 0.2 mg• iodoTMT6-128 Label Reagent, 5 x 0.2 mg• iodoTMT6-129 Label Reagent, 5 x 0.2 mg• iodoTMT6-130 Label Reagent, 5 x 0.2 mg• iodoTMT6-131 Label Reagent, 5 x 0.2 mgStore at –20°C.
Starting Material: Cell Lysate
Detection Method: Mass Spectrometry
Quantity: 5 x 0.2 mg (per tag)
For Use With (Equipment):
Mass Spectrometer
Product Line:
iodoTMTsixplex™
Label or Dye:
Tandem Mass Tag™ (TMT) Labels
Final Product Type:
Protein
Workflow Step:
Protein Labeling
Product Type:
Isobaric Label Reagent Set
Content And Storage:
Sufficient for: Five sixplex (5 x 6-way) experiments• iodoTMT6-126 Label Reagent, 5 x 0.2 mg• iodoTMT6-127 Label Reagent, 5 x 0.2 mg• iodoTMT6-128 Label Reagent, 5 x 0.2 mg• iodoTMT6-129 Label Reagent, 5 x 0.2 mg• iodoTMT6-130 Label Reagent, 5 x 0.2 mg• iodoTMT6-131 Label Reagent, 5 x 0.2 mgStore at –20°C.
Starting Material:
Cell Lysate
Detection Method:
Mass Spectrometry
Quantity:
5 x 0.2 mg (per tag)
For Use With (Equipment): Mass Spectrometer
Product Line: iodoTMTsixplex™
Label or Dye: Tandem Mass Tag™ (TMT) Labels
Final Product Type: Protein
Workflow Step: Protein Labeling
Product Type: __
Content And Storage: • iodoTMT6-126 Label Reagent, 5 x 0.2 mg• iodoTMT6-127 Label Reagent, 5 x 0.2 mg• iodoTMT6-128 Label Reagent, 5 x 0.2 mg• iodoTMT6-129 Label Reagent, 5 x 0.2 mg• iodoTMT6-130 Label Reagent, 5 x 0.2 mg• iodoTMT6-131 Label Reagent, 5 x 0.2 mg• HES Buffer, 15 mL• Bond-Breaker TCEP Solution, 0.5 mL• DTT, No-Weigh Format, 8 x 7.7 mg• Trypsin, 5 x 20 μg• Trypsin Storage Solution, 250 μL• Albumin (bovine), 2.5 mgUpon receipt store all products at –20°C
Starting Material: Cell Lysate
Detection Method: Mass Spectrometry
Quantity: 30 reactions
For Use With (Equipment):
Mass Spectrometer
Product Line:
iodoTMTsixplex™
Label or Dye:
Tandem Mass Tag™ (TMT) Labels
Final Product Type:
Protein
Workflow Step:
Protein Labeling
Product Type:
__
Content And Storage:
• iodoTMT6-126 Label Reagent, 5 x 0.2 mg• iodoTMT6-127 Label Reagent, 5 x 0.2 mg• iodoTMT6-128 Label Reagent, 5 x 0.2 mg• iodoTMT6-129 Label Reagent, 5 x 0.2 mg• iodoTMT6-130 Label Reagent, 5 x 0.2 mg• iodoTMT6-131 Label Reagent, 5 x 0.2 mg• HES Buffer, 15 mL• Bond-Breaker TCEP Solution, 0.5 mL• DTT, No-Weigh Format, 8 x 7.7 mg• Trypsin, 5 x 20 μg• Trypsin Storage Solution, 250 μL• Albumin (bovine), 2.5 mgUpon receipt store all products at –20°C
Starting Material:
Cell Lysate
Detection Method:
Mass Spectrometry
Quantity:
30 reactions
For Use With (Equipment): Mass Spectrometer
Product Line: TMT™
Label or Dye: Tandem Mass Tag™ (TMT) Labels
Final Product Type: Peptide
Workflow Step: Protein Labeling
Product Type: __
Content And Storage: Store at 4°C.
Starting Material: Cell Lysate
Detection Method: Mass Spectrometry
Quantity: 20 mL
For Use With (Equipment):
Mass Spectrometer
Product Line:
TMT™
Label or Dye:
Tandem Mass Tag™ (TMT) Labels
Final Product Type:
Peptide
Workflow Step:
Protein Labeling
Product Type:
__
Content And Storage:
Store at 4°C.
Starting Material:
Cell Lysate
Detection Method:
Mass Spectrometry
Quantity:
20 mL
For Use With (Equipment): __
Product Line: Pierce™
Label or Dye: __
Final Product Type: __
Workflow Step: __
Product Type: __
Content And Storage: Upon receipt store kit at –20°C, or store individual components as indicated above. Kit is shipped with an ice pack.
Starting Material: __
Detection Method: S-Nitrosylation
Quantity: 40 Reactions
For Use With (Equipment):
__
Product Line:
Pierce™
Label or Dye:
__
Final Product Type:
__
Workflow Step:
__
Product Type:
__
Content And Storage:
Upon receipt store kit at –20°C, or store individual components as indicated above. Kit is shipped with an ice pack.
Starting Material:
__
Detection Method:
S-Nitrosylation
Quantity:
40 Reactions