SAB4200617

Monoclonal Anti-Myb antibody from mouse

clone MB-8, purified immunoglobulin

Manufacturer: Sigma Aldrich

Synonym(S): Proto-oncogene c-Myb, Transcriptional activator Myb, Transcriptional activator Myb; Proto-oncogene c-Myb

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Pack Size SKU Availability Price
200 μL SAB4200617-200-μL In Stock ₹ 53,779.50

SAB4200617 - 200 μL

₹ 53,779.50

In Stock

Quantity

1

Base Price: ₹ 53,779.50

GST (18%): ₹ 9,680.31

Total Price: ₹ 63,459.81

biological source

mouse

Quality Level

200

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MB-8, monoclonal

species reactivity

human, mouse

concentration

~1 mg/mL

technique(s)

flow cytometry: 2.5-5 μg/test using using HL-60 cells.immunoblotting: 0.5-1 μg/mL using using Jurkat total cell extract.immunofluorescence: 2-4 μg/mL using using HeLa cells.

isotype

IgG1

UniProt accession no.

P10242

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Description

  • General description: Monoclonal Anti-Myb (mouse IgG1 isotype) is derived from the hybridoma MB-8 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. MYB proto-oncogene, transcription factor is encoded by the gene mapped to human chromosome 6q23.3.
  • Specificity: Monoclonal Anti-Myb recognizes human and mouse Myb.
  • Immunogen: synthetic peptide corresponding to a sequence at the N-terminal region of human Myb.
  • Application: Monoclonal Anti-Myb antibody from mouse may be used in:immunoblottingflow cytometryimmunocytochemistry
  • Biochem/physiol Actions: MYB is a transcription factor that regulates stem and progenitor cells in the bone marrow, colonic crypts and a neurogenic region of the adult brain. Loss of MYB activity in these cells leads to severe or lethal phenotypes. MYB is an oncogene and is observed in some human leukemias. In addition, It is also observed that MYB is activated in colon and breast cancer.
  • Physical form: Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
  • Storage and Stability: For extended storage, freeze at -20 ˚C in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
  • Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

SAFETY INFORMATION

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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