RAB0010

Angiotensin II EIA Kit

for serum, plasma, culture supernatant and cell lysates

Manufacturer: Sigma Aldrich

Synonym(S): Angiotensinogen, Serpin A8

Select a Size

Pack Size SKU Availability Price
1 KIT RAB0010-1-KIT In Stock ₹ 60,972.30

RAB0010 - 1 KIT

₹ 60,972.30

In Stock

Quantity

1

Base Price: ₹ 60,972.30

GST (18%): ₹ 10,975.014

Total Price: ₹ 71,947.314

species reactivity

mouse, human, rat

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitableenzyme immunoassay: suitable

input

sample type cell lysatesample type culture supernatant(s)sample type serumsample type plasma

assay range

inter-assay cv: <15%intra-assay cv: <10%sensitivity: 2.62 pg/mLstandard curve range: 0.1-1000 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... AGT(183)

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Description

  • General description: The Angiotensin II Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Angiotensin II peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANGII-1 can theoretically detect all active angiotensins, including ANGI, ANGII, ANGIII and ANGIV. However, it does not detect inactive angiotensinogen.
  • Immunogen: Angiotensin II, synthetic peptide
  • Application: Angiotensin II EIA Kit has been used for quantitative estimation of serum angiotensin-II.[1][2]
  • Biochem/physiol Actions: Study on in vitro model shows that mechanical stretch induced Ang II release plays a vital role in mediating stretch-induced hypertrophic response.[4] Ang II is implicated in maintaining blood pressure and has an important role in hypertension and in the pathophysiology of cardiovascular disorders. Ang II also has an essential role in growth induction, cell migration and mitosis of vascular smooth muscle cells. It enhances the production of collagen type I and III in fibroblasts, that results in thickening of the vascular wall and myocardium, and fibrosis. Variation in Ang II gene increases the risk of myocardial infarction, hypertension and left ventricular hypertrophy.[5] Ang II expression is associated with heart failure, cardiac remodeling, diabetes, and the proliferative and inflammatory responses to arterial injury. The pharmacological agents such as angiotensin II-converting enzyme inhibitors or angiotensin II receptor antagonists can be used for treating Ang II-induced hypertension and congestive heart failure.[6]

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

WGK

WGK 3

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Sigma Aldrich

RAB0010

for serum, plasma, culture supernat...


species reactivity:
mouse, human, rat

packaging:
kit of 96 wells (12 strips x 8 wells)

technique(s):
ELISA: suitableenzyme immunoassay: suitable

input:
sample type cell lysatesample type culture supernatant(s)sample type serumsample type plasma

assay range:
inter-assay cv: <15%intra-assay cv: <10%sensitivity: 2.62 pg/mLstandard curve range: 0.1-1000 ng/mL

detection method:
colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... AGT(183)

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RAB0011

for detection of human, mouse or ra...


species reactivity:
human, rat, mouse

packaging:
kit of 96 wells (12 strips x 8 wells)

technique(s):
ELISA: suitablecapture ELISA: suitable

input:
sample type cell lysatesample type tissue lysate

assay range:
__

detection method:
colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... AKT1(207)

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RAB0012

for detection of human, mouse or ra...


species reactivity:
human, mouse, rat

packaging:
kit of 96 wells (12 strips x 8 wells)

technique(s):
ELISA: suitablecapture ELISA: suitable

input:
sample type: human cell lysatesample type tissue lysate

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packaging:
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technique(s):
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input:
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assay range:
inter-assay cv: <12%intra-assay cv: <10%sensitivity: 15 pg/mLstandard curve range: 20.48-5000 pg/mL

detection method:
colorimetric

shipped in:
wet ice

storage temp.:
−20°C

Gene Information:
human ... ALCAM(214)