E9406

Epirubicin hydrochloride

≥90% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 56390-09-1

Synonym(S): 4′-Epidoxorubicin hydrochloride, Epidoxorubicin hydrochloride

Select a Size

Pack Size SKU Availability Price
5 MG E9406-5-MG In Stock ₹ 14,280.00
10 MG E9406-10-MG In Stock ₹ 38,470.00

E9406 - 5 MG

₹ 14,280.00

In Stock

Quantity

1

Base Price: ₹ 14,280.00

GST (18%): ₹ 2,570.40

Total Price: ₹ 16,850.40

biological source

synthetic

Quality Level

100

Assay

≥90% (HPLC)

form

powder

color

red to deep red

solubility

H2O: soluble

antibiotic activity spectrum

neoplastics

Mode of action

DNA synthesis | interferesenzyme | inhibits

storage temp.

−20°C

SMILES string

Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO

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Description

  • Application: Epirubicin is used to inhibit topoisomerase II and DNA helicase activity. Epirubicin is used to study metastatic breast cancer[1]and cardiac toxicity[2].
  • Biochem/physiol Actions: Epirubicin is antimitotic and cytotoxic. It inhibits nucleic acid and protein synthesis. Epirubicin may do so by forming complexes with DNA and intercalation between base pairs, by inhibiting topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, and by preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H340,H350,H360

Precautionary Statements

P201 - P301 + P312 + P330 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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≥90% (HPLC)...


biological source:
synthetic

Quality Level:
100

Assay:
≥90% (HPLC)

form:
powder

color:
red to deep red

solubility:
H2O: soluble

antibiotic activity spectrum:
neoplastics

Mode of action:
DNA synthesis | interferesenzyme | inhibits

storage temp.:
−20°C

SMILES string:
Cl.COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO

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