PC4211SET
MilliporeSigma™ Vanilloid Receptor Like Protein-1 (744-761), Rabbbit Polyclonal, ChIP Validated Antibody and Primer Set
Manufacturer: MilliporeSigma™
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Antigen
Vanilloid Receptor Like Protein-1 (744-761)
Classification
Polyclonal
Formulation
100μg antibody in 0.05 M sodium phosphate buffer, 0.2% gelatin and 25μg lyophilized control peptide (immunogen) (100μg size only).
Immunogen
a synthetic peptide (KNSASEEDHLPLQVLQSP) corresponding to amino acids 744-761 of rat vanilloid receptor like protein 1, conjugated to KLH
Regulatory Status
RUO
Test Specificity
Recognizes the ∽98kDa (doublet) vanilloid receptor like protein-1 in rat spinal cord extract. Supplied with a control peptide (100μg size only).
Target Species
Mouse, Rat
Form
Purified
Applications
Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen)
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
1 Set
Primary or Secondary
Primary
Includes
100μg antibody in 0.05M sodium phosphate buffer, 0.2% gelatin and 25μg lyophilized control peptide (immunogen) (100μg size only).
Content And Storage
2°C to 8°C
Isotype
IgG
Related Products
Description
- Specifically detects Vanilloid Receptor Like Protein-1 (744-761) Clone: in Mouse, Rat samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Frozen), Immuno Blotting The detection of noxious stimuli (chemical, mechanical, or thermal), a process referred to as nociception, occurs predominantly at the peripheral terminals of primary afferent neurons
- This information is ultimately transmitted to the central nervous system to evoke a perception of pain which initiates appropriate protective reflexes
- Vanilloid-containing compounds which include capsaicin, the active ingredient in hot chilli peppers, selectively depolarize nociceptors to activate the nociceptive pathway
- The receptor for capsaicin, vanilloid receptor 1 (VR1), has been identified as a nonselective cation channel that resembles members of the transient receptor potential (TRP) family of ion channels
- The vanilloid receptor 1 protein functions both as a receptor for capsaicin and a transducter of noxious thermal stimuli
- Immunocytochemical and mRNA localization studies suggest that VR1 protein is localized to small-diameter sensory neurons within the dorsal root ganglia and nerve terminals in the dorsal horn
- A capsaicin-receptor homolog has recently been identified, designated the vanilloid-receptor-like protein 1 (VRL-1)
- VRL-1 is activated by high temperatures and is expressed in medium- to large-diameter neurons within sensory ganglia.
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Antigen: Vanilloid Receptor Like Protein-1 (744-761)
Classification: Polyclonal
Formulation: 100μg antibody in 0.05 M sodium phosphate buffer, 0.2% gelatin and 25μg lyophilized control peptide (immunogen) (100μg size only).
Immunogen: a synthetic peptide (KNSASEEDHLPLQVLQSP) corresponding to amino acids 744-761 of rat vanilloid receptor like protein 1, conjugated to KLH
Regulatory Status: RUO
Test Specificity: Recognizes the ∽98kDa (doublet) vanilloid receptor like protein-1 in rat spinal cord extract. Supplied with a control peptide (100μg size only).
Target Species: Mouse, Rat
Form: Purified
Applications: Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen)
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 1 Set
Primary or Secondary: Primary
Includes: 100μg antibody in 0.05M sodium phosphate buffer, 0.2% gelatin and 25μg lyophilized control peptide (immunogen) (100μg size only).
Content And Storage: 2°C to 8°C
Isotype: IgG
Antigen:
Vanilloid Receptor Like Protein-1 (744-761)
Classification:
Polyclonal
Formulation:
100μg antibody in 0.05 M sodium phosphate buffer, 0.2% gelatin and 25μg lyophilized control peptide (immunogen) (100μg size only).
Immunogen:
a synthetic peptide (KNSASEEDHLPLQVLQSP) corresponding to amino acids 744-761 of rat vanilloid receptor like protein 1, conjugated to KLH
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽98kDa (doublet) vanilloid receptor like protein-1 in rat spinal cord extract. Supplied with a control peptide (100μg size only).
Target Species:
Mouse, Rat
Form:
Purified
Applications:
Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen)
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
1 Set
Primary or Secondary:
Primary
Includes:
100μg antibody in 0.05M sodium phosphate buffer, 0.2% gelatin and 25μg lyophilized control peptide (immunogen) (100μg size only).
Content And Storage:
2°C to 8°C
Isotype:
IgG
Antigen: Caspase-3, Cleaved
Classification: Polyclonal
Formulation: In PBS, 50% glycerol, 1% BSA, pH 7.2.
Immunogen: a synthetic peptide corresponding to amino acids surrounding the Asp175cleavage site of caspase-3
Regulatory Status: RUO
Test Specificity: Recognizes the ∽17kDa cleaved fragment of caspase-3.
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 50 μg
Primary or Secondary: Primary
Includes: __
Content And Storage: ≤ -70°C
Isotype: IgG
Antigen:
Caspase-3, Cleaved
Classification:
Polyclonal
Formulation:
In PBS, 50% glycerol, 1% BSA, pH 7.2.
Immunogen:
a synthetic peptide corresponding to amino acids surrounding the Asp175cleavage site of caspase-3
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽17kDa cleaved fragment of caspase-3.
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
50 μg
Primary or Secondary:
Primary
Includes:
__
Content And Storage:
≤ -70°C
Isotype:
IgG
Antigen: MYH (33-51)
Classification: Polyclonal
Formulation: Undiluted serum.
Immunogen: a synthetic peptide (QEGRQKHAKNNSQAKPSAC) corresponding to amino acids 33-51 of human MYH
Regulatory Status: RUO
Test Specificity: Recognizes the MYH protein and several of its approximately 10 isoforms in PC12, Jurkat, and HeLa cells.
Target Species: Human, Rat
Form: Undiluted
Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Includes: __
Content And Storage: −20°C
Isotype: IgG
Antigen:
MYH (33-51)
Classification:
Polyclonal
Formulation:
Undiluted serum.
Immunogen:
a synthetic peptide (QEGRQKHAKNNSQAKPSAC) corresponding to amino acids 33-51 of human MYH
Regulatory Status:
RUO
Test Specificity:
Recognizes the MYH protein and several of its approximately 10 isoforms in PC12, Jurkat, and HeLa cells.
Target Species:
Human, Rat
Form:
Undiluted
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Includes:
__
Content And Storage:
−20°C
Isotype:
IgG
Antigen: CHIP
Classification: Polyclonal
Formulation: Undiluted serum.
Immunogen: a recombinant protein consisting of full-length human CHIP fused to a His·Tag™ sequence
Regulatory Status: RUO
Test Specificity: Recognizes the ∽35kDa CHIP protein. May also detect bands at ∽43, ∽51, and ∽70kDa corresponding to the mono-ubiquitinated, di-ubiquitinated, and dimeric forms of CHIP, respectively.
Target Species: Drosophila, Hamster, Human, Monkey, Mouse, Rat
Form: Undiluted
Applications: Immunofluorescence, Immunoprecipitation
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Includes: __
Content And Storage: −20°C
Isotype: IgG
Antigen:
CHIP
Classification:
Polyclonal
Formulation:
Undiluted serum.
Immunogen:
a recombinant protein consisting of full-length human CHIP fused to a His·Tag™ sequence
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽35kDa CHIP protein. May also detect bands at ∽43, ∽51, and ∽70kDa corresponding to the mono-ubiquitinated, di-ubiquitinated, and dimeric forms of CHIP, respectively.
Target Species:
Drosophila, Hamster, Human, Monkey, Mouse, Rat
Form:
Undiluted
Applications:
Immunofluorescence, Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Includes:
__
Content And Storage:
−20°C
Isotype:
IgG