14-900-882
Phospho-STAT1 (Tyr701) Monoclonal Antibody (KIKSI0803), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 14-900-882-Each | In Stock | ₹ 32,987.85 |
14-900-882 - Each
In Stock
Quantity
1
Base Price: ₹ 32,987.85
GST (18%): ₹ 5,937.813
Total Price: ₹ 38,925.663
Antigen
Phospho-STAT1 (Tyr701)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P42224
Gene Symbols
STAT1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6772
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Western Blot
Clone
KIKSI0803
Conjugate
Unconjugated
Gene
STAT1
Gene Alias
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- This KIKSI0803 MAb recognizes signal transducer and activator of transcription 1 (STAT1) when phosphorylated on tyrosine 701
- STAT proteins are activated by ligand binding to receptors, such as cytokine receptors, that associate with Janus kinase (JAK) family members
- Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner
- Phosphorylation of STAT1 on tyrosine 701 by JAK1 and JAK2 is essential for STAT1 dimer formation, nuclear translocation, and DNA binding activity
- In response to IFN gamma stimulation, STAT1 homodimerizes or forms heterodimers with STAT3 that can bind to GAS (IFN gamma-activated sequence) promoter elements
- In response to either IFN alpha or IFN beta stimulation, STAT1 forms a heterodimer with STAT2 that can bind ISRE (IFN-stimulated response element) promoter elements
- STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors
- STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6
- STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism
- Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure
- The STAT1 gene is located on chromosome 2
- STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors
- After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes
- Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile
- STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1)
- Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described.
Compare Similar Items
Show Difference
Antigen: Phospho-STAT1 (Tyr701)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P42224
Gene Symbols: STAT1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6772
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: KIKSI0803
Conjugate: Unconjugated
Gene: STAT1
Gene Alias: 2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Phospho-STAT1 (Tyr701)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P42224
Gene Symbols:
STAT1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6772
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
KIKSI0803
Conjugate:
Unconjugated
Gene:
STAT1
Gene Alias:
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD281 (TLR1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9EPQ1
Gene Symbols: TLR1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21897
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunoprecipitation
Clone: eBioTR23 (TR23)
Conjugate: Unconjugated
Gene: TLR1
Gene Alias: CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; TLR1; toll like receptor 1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1
Host Species: Rat
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD281 (TLR1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9EPQ1
Gene Symbols:
TLR1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21897
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunoprecipitation
Clone:
eBioTR23 (TR23)
Conjugate:
Unconjugated
Gene:
TLR1
Gene Alias:
CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; TLR1; toll like receptor 1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1
Host Species:
Rat
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Phospho-BTK/ITK (Tyr551, Tyr511)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P35991, Q03526, Q06187, Q08881
Gene Symbols: BTK, ITK
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12229, 16428, 3702, 695
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: M4G3LN
Conjugate: Unconjugated
Gene: ITK
Gene Alias: agammaglobulinaemia tyrosine kinase; agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; bruton tyrosine kinase; Bruton's tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; Emt; homolog of mouse T-cell itk/tsk; IL2 inducible T cell kinase; IL2 inducible T-cell kinase; IL-2-inducible T cell kinase; IL-2-inducible T-cell kinase; IL2-inducible T-cell kinase; IMD1; interleukin-2-inducible T cell kinase; interleukin-2-inducible T-cell kinase; ITK; Kinase EMB; kinase EMT; Kinase TLK; LPFS1; LYK; PSCTK1; PSCTK2; T-cell-specific kinase; Tcsk; Tlk; truncated Bruton agammaglobulinemia tyrosine kinase; Tsk; Tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking e
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
Phospho-BTK/ITK (Tyr551, Tyr511)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P35991, Q03526, Q06187, Q08881
Gene Symbols:
BTK, ITK
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12229, 16428, 3702, 695
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
M4G3LN
Conjugate:
Unconjugated
Gene:
ITK
Gene Alias:
agammaglobulinaemia tyrosine kinase; agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; bruton tyrosine kinase; Bruton's tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; Emt; homolog of mouse T-cell itk/tsk; IL2 inducible T cell kinase; IL2 inducible T-cell kinase; IL-2-inducible T cell kinase; IL-2-inducible T-cell kinase; IL2-inducible T-cell kinase; IMD1; interleukin-2-inducible T cell kinase; interleukin-2-inducible T-cell kinase; ITK; Kinase EMB; kinase EMT; Kinase TLK; LPFS1; LYK; PSCTK1; PSCTK2; T-cell-specific kinase; Tcsk; Tlk; truncated Bruton agammaglobulinemia tyrosine kinase; Tsk; Tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking e
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD266 (TWEAK Receptor)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9NP84
Gene Symbols: TNFRSF12A
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51330
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
Clone: ITEM-1
Conjugate: Unconjugated
Gene: TNFRSF12A
Gene Alias: AI255180; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12A; TNFRSF12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14
Host Species: Mouse
Quantity: 2 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD266 (TWEAK Receptor)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9NP84
Gene Symbols:
TNFRSF12A
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51330
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
Clone:
ITEM-1
Conjugate:
Unconjugated
Gene:
TNFRSF12A
Gene Alias:
AI255180; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12A; TNFRSF12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14
Host Species:
Mouse
Quantity:
2 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ