14-969-282

HCN2 Monoclonal Antibody (QQA 4A6), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 14-969-282-Each-of-1 In Stock ₹ 42,780.00

14-969-282 - Each of 1

₹ 42,780.00

In Stock

Quantity

1

Base Price: ₹ 42,780.00

GST (18%): ₹ 7,700.40

Total Price: ₹ 50,480.40

Antigen

HCN2

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.

O88703, Q9JKA9

Gene Symbols

HCN2

Immunogen

Peptide corresponding to aa676-710

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunohistochemistry (Frozen), Western Blot

Clone

QQA 4A6

Conjugate

Unconjugated

Gene

HCN2

Gene Alias

BCNG2, BCNG-2, brain cyclic nucleotide gated channel 2, brain cyclic nucleotide-gated channel 2, Hac1, HAC-1, HCN2, hyperpolarization activated cyclic nucleotide gated potassium channel 2, hyperpolarization activated cyclic nucleotide-gated potassium channel 2, hyperpolarization-activated cation channel 1, hyperpolarization-activated, cyclic nucleotide-gated K+ 2, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, trls

Host Species

Rat

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

114244, 15166

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • Description: This QQA 4A6 monoclonal antibody recognizes mouse and rat HCN2
  • QQA 4A6 detects a ∽95 kDa band corresponding to HCN2 by Western Blot
  • An off target band of ∽80 kDa is detected in cell line models
  • Applications Reported: This QQA 4A6 antibody has been reported for use in western blot and immunohistochemical staining
  • Applications Tested: This QQA 4A6 antibody has been tested by western blot and may be used at less than or equal to 1.0 μg/mL The QQA 4A6 antibody has been tested by immunohistochemistry of frozen mouse tissue sections and can be used at less than or equal to 40 μg/mL
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Hyperpolarization-activated cation channels of the HCN gene family such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain
  • HCN2 is a member of a family of pacemaker channels activated by hyperpolarization and regulated by cyclic nucleotides
  • HCN1 and HCN2 play an important role for motor learning and neuronal integration by cerebellar Purkinje cells; as well as, shaping autonomous activity of single neurons and the periodicity of network oscillations
  • The HCN1 expression is highly enriched in cerebral cortex, hippocampus, cerebellum, and facial motor nucleus
  • HCN2 is highly abundant in mamillary bodies, pontine nucleus, ventral cochlear nucleus, and nucleus of the trapezoid body
  • These variations in regional specificity of HCN channels could generate important differences in neuronal pacemaker activity across brain systems.

Compare Similar Items

Show Difference

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Invitrogen

14-969-282

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Antigen:
HCN2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
O88703, Q9JKA9

Gene Symbols:
HCN2

Immunogen:
Peptide corresponding to aa676-710

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Frozen), Western Blot

Clone:
QQA 4A6

Conjugate:
Unconjugated

Gene:
HCN2

Gene Alias:
BCNG2, BCNG-2, brain cyclic nucleotide gated channel 2, brain cyclic nucleotide-gated channel 2, Hac1, HAC-1, HCN2, hyperpolarization activated cyclic nucleotide gated potassium channel 2, hyperpolarization activated cyclic nucleotide-gated potassium channel 2, hyperpolarization-activated cation channel 1, hyperpolarization-activated, cyclic nucleotide-gated K+ 2, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, trls

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114244, 15166

Content And Storage:
4° C, do not freeze

Form:
Liquid

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Fischer Scientific

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Antigen:
Globo H

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with proprietary stabilizer and 0.09% sodium azide; pH 7.2

Gene Accession No.:
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Gene Symbols:
__

Immunogen:
__

Quantity:
2 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG3 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
VK9

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Globo H antigen; globoH; Globohexaosylceramide

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

14-970-095

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Antigen:
Globo H

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with proprietary stabilizer and 0.09% sodium azide; pH 7.2

Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Quantity:
10 mg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG3 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
VK9

Conjugate:
Unconjugated

Gene:
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Gene Alias:
Globo H antigen; globoH; Globohexaosylceramide

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
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Content And Storage:
4° C

Form:
Liquid

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Antigen:
OCT1 (POU2F1)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide, pH 7.2

Gene Accession No.:
P14859

Gene Symbols:
POU2F1

Immunogen:
Recombinant full-length human OCT1 (POU2F1)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
YL15

Conjugate:
Unconjugated

Gene:
POU2F1

Gene Alias:
2810482H01Rik, NF-A1, OCT1, oct-1, oct-1B, octamer binding protein 1, octamer-binding protein 1, Octamer-binding transcription factor 1, Octamer-binding transcription factor-1, Otf1, OTF-1, POU class 2 homeobox 1, POU domain, class 2, transcription factor 1, Pou2f1, ubiquitous transcription factor

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5451

Content And Storage:
4° C, do not freeze

Form:
Liquid