3970467

Connexin-43 Mouse, Unlabeled, Clone: 2, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Connexin-43

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Clone

2

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Chicken, Human, Mouse, Rat

Immunogen

Rat Connexin-43 aa. 252-270

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Gap junctions are intercellular protein pores
  • They enable cell-to-cell communication by allowing passage of ions and other small molecules
  • The subunits of gap junction channels are assembled from a family of proteins called connexins
  • Individual connexin molecules join to make hexameric hemichannels termed connexons; these structures dock to connexons on neighboring cells, forming gap junction pores
  • Connexin-43 is a member of the connexin family possessing four transmembrane regions, with cytoplasmic amino and carboxyl terminals
  • It undergoes rapid turnover in the cell and its monomers may reside in the ER/Golgi network, forming a reservoir available for assembly upon degradation of existing connexin-43 channels
  • In addition, it is believed that phosphorylation of connexin-43 plays a regulatory role both in the assembly of connexons and in gating activity at the gap junction
  • Host Species: Mouse Clone: 2 Isotype: IgG2 Species Reactivity: Rat Immunogen: Rat Connexin-43 aa
  • 252-270 Formula Weight [Chemical]: 43kDa Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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3970467

Mouse Monoclonal Antibody...


Antigen:
Connexin-43

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
2

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
Rat Connexin-43 aa. 252-270

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
Crk

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
Affinity Purified

Clone:
22

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat

Immunogen:
Human Crk aa. 102 to 304

Primary or Secondary:
Primary

Content And Storage:
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Antigen:
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Concentration:
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Classification:
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Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
Affinity Purified

Clone:
22

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat

Immunogen:
Human Crk aa. 102 to 304

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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