3970470
Crk Mouse, Unlabeled, Clone: 22, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Crk
Concentration
250μg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype
IgG2a
Purification Method
Affinity Purified
Clone
22
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat
Immunogen
Human Crk aa. 102 to 304
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Related Products
Description
- Crk was first isolated as the v- crk oncogene from chicken retroviruses CT10 and ASV-1
- All human cell lines examined to date express a 40 kDa Crk protein
- In addition, there is variable expression of 42 kDa and 28 kDa Crk proteins
- The c- crk gene is one of a class of genes, such as Nck and GRB2/ASH , which encode proteins that consist mainly of SH2 and SH3 domains
- These proteins function as adaptor molecules in tyrosine kinase signal transduction pathways
- The SH2 domains interact with phosphotyrosine-containing peptides, while the SH3 domains can enhance this interaction and/or bind to other cellular components
- Both the SH2 and SH3 domains of the human Crk protein are required for differentiation of PC12 cells
- Thus, Crk has a role in an NGF-induced signaling pathway that involves activation of p21ras
- Furthermore, three proteins of 118 kDa, 125 kDa, and 136 kDa which specifically bind to the Crk SH3 domain have been identified.
Compare Similar Items
Show Difference
Antigen: Crk
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG2a
Purification Method: Affinity Purified
Clone: 22
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Bovine, Canine, Chicken, Frog, Human, Mouse, Rat
Immunogen: Human Crk aa. 102 to 304
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Crk
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG2a
Purification Method:
Affinity Purified
Clone:
22
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat
Immunogen:
Human Crk aa. 102 to 304
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: __
Concentration: __
Classification: __
Host Species: __
Research Discipline: __
Formulation: __
Isotype: __
Purification Method: __
Clone: __
Applications: __
Conjugate: __
Regulatory Status: __
Target Species: __
Immunogen: __
Primary or Secondary: __
Content And Storage: __
Antigen:
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Concentration:
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Classification:
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Host Species:
__
Research Discipline:
__
Formulation:
__
Isotype:
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Purification Method:
__
Clone:
__
Applications:
__
Conjugate:
__
Regulatory Status:
__
Target Species:
__
Immunogen:
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Primary or Secondary:
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Content And Storage:
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Antigen: Cyclin A
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 25
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Immunogen: Human Cyclin A aa. 26-144
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Cyclin A
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
25
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
Human Cyclin A aa. 26-144
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Cyclin A
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 25
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Immunogen: Human Cyclin A aa. 26-144
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Cyclin A
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
25
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
Human Cyclin A aa. 26-144
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.