3971715
Phospholipase Cγ1 Mouse, Unlabeled, Clone: 10/PLCGAMMA, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Phospholipase Cγ1
Concentration
250μg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Clone
10/PLCGAMMA
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Canine, Chicken, Human, Mouse, Rat
Isotype
IgG1
Purification Method
Affinity Purified
Related Products
Description
- Description The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositol biphosphate to inositol triphosphate and diacylglycerol
- The former causes release of calcium from the endoplasmic reticulum, while the latter is an activator of Protein Kinase C
- Within the PLC family, PLCγ is the only member that contains SH2 and SH3 domains
- These domains enable it to interact with receptor tyrosine kinases and become enzymatically activated via phosphorylation
- It exists as two isoforms: 1) PLCγ 1, which is ubiquitously expressed, and 2) PLCγ 2, found primarily in the lymphoid system
- PLCγ is essential for growth factor-induced cell motility and mitogenesis
- PLCγ 1 null mice exhibit retarded embryonic growth and lethality in midgestation
- Overexpression of PLCγ is evident in several forms of cancer, and it has been identified as a key mediator of PDGF-dependent cellular transformation
- Thus regulation of PLCγ activity by growth factors is involved in cell growth and transformation.
Compare Similar Items
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Antigen: Phospholipase Cγ1
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Clone: 10/PLCGAMMA
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Chicken, Human, Mouse, Rat
Isotype: IgG1
Purification Method: Affinity Purified
Antigen:
Phospholipase Cγ1
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Clone:
10/PLCGAMMA
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Chicken, Human, Mouse, Rat
Isotype:
IgG1
Purification Method:
Affinity Purified
Antigen: Phosphotyrosine
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA and glycerol.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: PY20
Applications: Western Blot
Conjugate: HRP
Regulatory Status: RUO
Target Species: Canine, Chicken, Frog, Human, Mouse, Rat
Isotype: IgG2b
Purification Method: Affinity Purified
Antigen:
Phosphotyrosine
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA and glycerol.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
PY20
Applications:
Western Blot
Conjugate:
HRP
Regulatory Status:
RUO
Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat
Isotype:
IgG2b
Purification Method:
Affinity Purified
Antigen: Phosphotyrosine
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA and glycerol.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: PY20
Applications: Western Blot
Conjugate: HRP
Regulatory Status: RUO
Target Species: Canine, Chicken, Frog, Human, Mouse, Rat
Isotype: IgG2b
Purification Method: Affinity Purified
Antigen:
Phosphotyrosine
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA and glycerol.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
PY20
Applications:
Western Blot
Conjugate:
HRP
Regulatory Status:
RUO
Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat
Isotype:
IgG2b
Purification Method:
Affinity Purified
Antigen: Phosphotyrosine
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA and glycerol.
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone: PY20
Applications: Western Blot
Conjugate: HRP
Regulatory Status: RUO
Target Species: Canine, Chicken, Frog, Human, Mouse, Rat
Isotype: IgG2b
Purification Method: Affinity Purified
Antigen:
Phosphotyrosine
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA and glycerol.
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone:
PY20
Applications:
Western Blot
Conjugate:
HRP
Regulatory Status:
RUO
Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat
Isotype:
IgG2b
Purification Method:
Affinity Purified