3971736

PI3-Kinase Mouse, Unlabeled, Clone: 4, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PI3-Kinase

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG2a

Purification Method

Affinity Purified

Clone

4

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Chicken, Human, Mouse, Rat

Immunogen

Human PI3-Kinase α subunit aa. 562 to 724

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • PI3-kinase phosphorylates the D-3 position of the inositol ring of phosphatidylinositol (PtdIns), PtdIns(4)P and PtdIns(4,5)P2 to produce the respective PI3-phosphorylated derivatives
  • PI3-kinase exists as a heterodimer of 85 kDa (p85) and 110 kDa (p110) subunits
  • The p85 subunit contains two SH2 domains and an SH3 domain
  • It associates with and serves as a substrate for activated growth factor receptor tyrosine kinases
  • p85 may serve as regulator of the catalytic subunit, p110, by acting as the link between PI3-kinase and the ligand-activated receptor
  • Two distinct forms of the p85 subunit have been described: 1) p85 α; , which binds tightly to the catalytic subunit, and 2) p85ß, a protein whose function is presently unknown
  • Both isoforms bind to activated receptors and serve as tyrosine kinase substrates.

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Fischer Scientific

3971736

Mouse Monoclonal Antibody...


Antigen:
PI3-Kinase

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
Affinity Purified

Clone:
4

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
Human PI3-Kinase α subunit aa. 562 to 724

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Mouse Monoclonal Antibody...


Antigen:
PKCα

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Clone:
3/PKC

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Immunogen:
Human PKCα aa. 270-427

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Mouse Monoclonal Antibody...


Antigen:
PKCα

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2b κ

Purification Method:
Affinity Purified

Clone:
3/PKC

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Immunogen:
Human PKCα aa. 270-427

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
PKCθ

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Clone:
27

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Human

Immunogen:
Human PKCθ aa. 21-217

Primary or Secondary:
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Content And Storage:
Store undiluted at -20°C.