3971693

Paxillin Mouse, Unlabeled, Clone: 349, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Paxillin

Concentration

1.0mg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing glycerol and ≤0.09% sodium azide.

Isotype

IgG1

Purification Method

Affinity Purified

Clone

349

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Chicken, Human, Mouse, Rat

Immunogen

Chicken Paxillin aa. 1 to 557

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • A number of cytoskeletal proteins are tyrosine phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts
  • One of these is the 68 kDa paxillin protein
  • Paxillin is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers
  • It is also present in the focal adhesions of Madin-Darby canine kidney epithelial cells, but is absent from the cell adherens junctions of these cells
  • Paxillin purified from chicken gizzard migrates as a diffuse band on SDS-PAGE with molecular weight of 65-70 kDa
  • It binds to the rod domain of vinculin, another focal adhesion protein
  • It is thought that phosphorylation of paxillin may have a role in that disassembly of focal adhesions and stress fibers during transformation.

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Fischer Scientific

3971693

Mouse Monoclonal Antibody...


Antigen:
Paxillin

Concentration:
1.0mg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing glycerol and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
349

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
Chicken Paxillin aa. 1 to 557

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Fischer Scientific

3971715

Mouse Monoclonal Antibody...


Antigen:
Phospholipase Cγ1

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
10/PLCGAMMA

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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3971715

Mouse Monoclonal Antibody...


Antigen:
Phospholipase Cγ1

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Clone:
10/PLCGAMMA

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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3971725

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Antigen:
Phosphotyrosine

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA and glycerol.

Isotype:
IgG2b

Purification Method:
Affinity Purified

Clone:
PY20

Applications:
Western Blot

Conjugate:
HRP

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.