4358224

CD3 Mouse anti-Human, Brilliant Violet 421, Clone: UCHT1, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD3

Applications

Flow Cytometry

Conjugate

Brilliant Violet 421

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon

Clone

UCHT1

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex
  • CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes
  • Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody
  • CD3 plays a central role in signal transduction during antigen recognition
  • The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.The antibody was conjugated to Brilliant Violet 421 and has been developed in collaboration with Sirigen
  • With an Ex Max of 407-nm and Em Max at 421-nm, Brilliant Violet 421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter)
  • Brilliant Violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates
  • Host Species: Mouse Clone: UCHT1 Isotype: IgG1, κ Species Reactivity: Human Immunogen: Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor Flow Cytometry

Compare Similar Items

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Fischer Scientific

4358224

Mouse Monoclonal Antibody...


Antigen:
CD3

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon

Clone:
UCHT1

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

Fischer Scientific

4358228

Mouse Monoclonal Antibody...


Antigen:
CD86

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72

Clone:
2331 (FUN-1)

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human HBL-1 Cell Line

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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4358229

Mouse Monoclonal Antibody...


Antigen:
CD8

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32

Clone:
RPA-T8

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Baboon, Cynomolgus, Human, Rhesus Monkey

Immunogen:
Human CD8a

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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4358230

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Antigen:
CD19

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 421

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
B4; B-lymphocyte antigen CD19; Leu-12

Clone:
HIB19

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.