4551503

Laminin B2/γ1 Ab-1 Rat Monoclonal Antibody, Epredia™

Recommended for Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded), Immunofluorescence and Immunoprecipitation (Native and denatured), Epredia™ Laminin B2/γ1 Ab-1, Rat Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: Fischer Scientific

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Antigen

Laminin B2/gamma1 Ab-1

Applications

Immunohistochemistry (Frozen), Immunoprecipitation

Host Species

Rat

Research Discipline

Extracellular Matrix

Immunogen

Murine EHS laminin preparation

Primary or Secondary

Primary

Clone

A5

Classification

Monoclonal

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

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Description

  • Laminins are large heterotrimeric, noncollagenous glycoproteins composed of α, β, and γ chains
  • They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM
  • Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms
  • Host Species: Rat Clone: A5 Isotype: IgG2a/κ Species Reactivity: Human and Mouse
  • Others not known
  • Epitope: Not determined Immunogen: Murine EHS laminin preparation Molecular Weight: ∽210kDa Positive Control: LS174T cells, Normal colon or colon CA Cellular Localization: Basement membrane Specificity of Ab-1 was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs
  • Ab-1 stains uniformly all human and murine basement membranes
  • Recommended for: Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded) Immunofluorescence Immunoprecipitation (Native and denatured) Note: USA: RUO; Int'l: RUO

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Antigen:
Laminin B2/gamma1 Ab-1

Applications:
Immunohistochemistry (Frozen), Immunoprecipitation

Host Species:
Rat

Research Discipline:
Extracellular Matrix

Immunogen:
Murine EHS laminin preparation

Primary or Secondary:
Primary

Clone:
A5

Classification:
Monoclonal

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

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Antigen:
LRP/MVP (Major Vault Protein) Ab-2

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Host Species:
Mouse

Research Discipline:
Cancer and Tumor Biology

Immunogen:
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells

Primary or Secondary:
Primary

Clone:
1032

Classification:
Monoclonal

Regulatory Status:
RUO

Target Species:
Human, Rat

Isotype:
IgG2a κ

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Antigen:
LRP/MVP (Major Vault Protein) Ab-2

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Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

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Mouse

Research Discipline:
Cancer and Tumor Biology

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Primary

Clone:
1032

Classification:
Monoclonal

Regulatory Status:
RUO

Target Species:
Human, Rat

Isotype:
IgG2a κ

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Clone:
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Classification:
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Regulatory Status:
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Target Species:
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Isotype:
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