53-575-582
CD169 (Siglec-1) Monoclonal Antibody (SER-4), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 53-575-582-Each-of-1 | In Stock | ₹ 33,282.84 |
53-575-582 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,282.84
GST (18%): ₹ 5,990.911
Total Price: ₹ 39,273.751
Antigen
CD169 (Siglec-1)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.
Q62230
Gene Symbols
SIGLEC1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20612
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
SER-4
Conjugate
Alexa Fluor 488
Gene
SIGLEC1
Gene Alias
Cd169, dJ1009E24.1, macrophage receptor, p210, pSn, SA, SER, sheep erythrocyte receptor, sialic acid binding Ig like lectin 1, sialic acid binding Ig-like lectin 1, sialoadhesin, Sialic acid-binding Ig-like lectin 1, sialic acid-binding immunoglobulin-like lectin 1, sialoadhesin, SIGLEC1, Siglec-1, SN
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The SER-4 monoclonal antibody reacts with mouse CD169, which is also known as Sialoadhesin and Siglec-1
- CD169 is a 185-kDa member of the Siglec family of adhesion and endocytic receptors that recognize sialylated glycans
- This receptor is expressed on a subset of macrophages that are found with high frequency in the spleen, liver, lymph node, and bone marrow
- CD169 can also be detected on monocytes in the bone marrow and periphery
- This receptor plays a role in cell-cell adhesion, as well as internalization of sialylated virus and bacteria
- This endocytic pathway allows CD169+ macrophages to present lipid antigens to iNKT cells, thereby leading to their activation
- Studies have also demonstrated direct interaction of CD169 with regulatory T cells inhibits their proliferation
- The SER-4 antibody has been reported to have antagonist activity
- Applications Reported: This SER-4 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This SER-4 antibody has been tested by flow cytometric analysis of mouse bone marrow cells
- This may be used at less than or equal to 1.0 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions
- Family members include sialoadhesin, CD22 and CD33
- Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.
Compare Similar Items
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Antigen: CD169 (Siglec-1)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q62230
Gene Symbols: SIGLEC1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20612
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: SER-4
Conjugate: Alexa Fluor 488
Gene: SIGLEC1
Gene Alias: Cd169, dJ1009E24.1, macrophage receptor, p210, pSn, SA, SER, sheep erythrocyte receptor, sialic acid binding Ig like lectin 1, sialic acid binding Ig-like lectin 1, sialoadhesin, Sialic acid-binding Ig-like lectin 1, sialic acid-binding immunoglobulin-like lectin 1, sialoadhesin, SIGLEC1, Siglec-1, SN
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD169 (Siglec-1)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q62230
Gene Symbols:
SIGLEC1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20612
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
SER-4
Conjugate:
Alexa Fluor 488
Gene:
SIGLEC1
Gene Alias:
Cd169, dJ1009E24.1, macrophage receptor, p210, pSn, SA, SER, sheep erythrocyte receptor, sialic acid binding Ig like lectin 1, sialic acid binding Ig-like lectin 1, sialoadhesin, Sialic acid-binding Ig-like lectin 1, sialic acid-binding immunoglobulin-like lectin 1, sialoadhesin, SIGLEC1, Siglec-1, SN
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: Endomucin
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.: Q9R0H2
Gene Symbols: Emcn
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 59308
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: eBioV.7C7 (V.7C7)
Conjugate: Alexa Fluor 488
Gene: Emcn
Gene Alias: 0610012K22Rik, AI315669, Emcn, EMCN2, Endomucin, endomucin-1, endomucin-1/2, Endomucin-2, gastric cancer antigen Ga34, Muc14, MUC-14, mucin 14, endothelial, mucin-14, sialomucin
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
Endomucin
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Accession No.:
Q9R0H2
Gene Symbols:
Emcn
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
59308
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eBioV.7C7 (V.7C7)
Conjugate:
Alexa Fluor 488
Gene:
Emcn
Gene Alias:
0610012K22Rik, AI315669, Emcn, EMCN2, Endomucin, endomucin-1, endomucin-1/2, Endomucin-2, gastric cancer antigen Ga34, Muc14, MUC-14, mucin 14, endothelial, mucin-14, sialomucin
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: TIM-4
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q6U7R4
Gene Symbols: TIMD4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 276891
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 54 (RMT4-54)
Conjugate: Alexa Fluor 488
Gene: TIMD4
Gene Alias: B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
Host Species: Rat
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
TIM-4
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q6U7R4
Gene Symbols:
TIMD4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
276891
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
54 (RMT4-54)
Conjugate:
Alexa Fluor 488
Gene:
TIMD4
Gene Alias:
B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
Host Species:
Rat
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: TIM-4
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q6U7R4
Gene Symbols: TIMD4
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 276891
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: 54 (RMT4-54)
Conjugate: Alexa Fluor 488
Gene: TIMD4
Gene Alias: B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
TIM-4
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q6U7R4
Gene Symbols:
TIMD4
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
276891
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
54 (RMT4-54)
Conjugate:
Alexa Fluor 488
Gene:
TIMD4
Gene Alias:
B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ