Mouse Monoclonal Antibody has been used in 1 publication
Manufacturer: Fischer Scientific
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Androgen R/NR3C4
0.2mg/mL
Immunohistochemistry (Paraffin), Immunofluorescence
Unconjugated
Mouse
Breast Cancer, Cancer, Cellular Markers
1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
AR
IgG
Protein A or G purified
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.
AR441 + DHTR/882
Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Monoclonal
Purified
RUO
Human, Mouse (Negative)
P10275
367
A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR (AR441); Recombinant human DHTR protein (DHTR/882)
Primary
Store at 4C.
110 kDa