5540504

Androgen R/NR3C4 Antibody (AR441 + DHTR/882), Novus Biologicals™

Mouse Monoclonal Antibody has been used in 1 publication

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Androgen R/NR3C4

Concentration

0.2mg/mL

Applications

Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Breast Cancer, Cancer, Cellular Markers

Formulation

1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

Gene Symbols

AR

Isotype

IgG

Purification Method

Protein A or G purified

Test Specificity

Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

Clone

AR441 + DHTR/882

Dilution

Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human, Mouse (Negative)

Gene Accession No.

P10275

Gene ID (Entrez)

367

Immunogen

A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR (AR441); Recombinant human DHTR protein (DHTR/882)

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Molecular Weight of Antigen

110 kDa

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Description

  • Ensure accurate, reproducible results in Immunohistochemistry (Paraffin), Immunofluorescence Androgen R/NR3C4 Monoclonal specifically detects Androgen R/NR3C4 in Human, Mouse (Negative) samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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5540504

Mouse Monoclonal Antibody has been ...


Antigen:
Androgen R/NR3C4

Concentration:
0.2mg/mL

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Breast Cancer, Cancer, Cellular Markers

Formulation:
1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

Gene Symbols:
AR

Isotype:
IgG

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

Clone:
AR441 + DHTR/882

Dilution:
Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse (Negative)

Gene Accession No.:
P10275

Gene ID (Entrez):
367

Immunogen:
A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR (AR441); Recombinant human DHTR protein (DHTR/882)

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
110 kDa

Img

Fischer Scientific

5540506

Mouse Monoclonal Antibody...


Antigen:
Androgen R/NR3C4

Concentration:
0.2mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Breast Cancer, Cancer, Cellular Markers

Formulation:
1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

Gene Symbols:
AR

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

Clone:
DHTR/882

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse (Negative)

Gene Accession No.:
P10275

Gene ID (Entrez):
367

Immunogen:
Recombinant full-length human DHTR protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
110 kDa

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5540529

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Antigen:
Arginase 1/ARG1/liver Arginase

Concentration:
0.2mg/mL

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Cellular Markers, Chromatin Research, Lipid and Metabolism

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase

Gene Symbols:
ARG1

Isotype:
IgG3 κ

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Clone:
ARG1/1125

Dilution:
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 1 - 2 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
P05089

Gene ID (Entrez):
383

Immunogen:
Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
36.5 kDa

Img

Fischer Scientific

5540529

Mouse Monoclonal Antibody...


Antigen:
Arginase 1/ARG1/liver Arginase

Concentration:
0.2mg/mL

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cancer, Cellular Markers, Chromatin Research, Lipid and Metabolism

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase

Gene Symbols:
ARG1

Isotype:
IgG3 κ

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Clone:
ARG1/1125

Dilution:
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 1 - 2 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Accession No.:
P05089

Gene ID (Entrez):
383

Immunogen:
Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Molecular Weight of Antigen:
36.5 kDa