7069513
Smooth Muscle Myosin Monoclonal Antibody (SMMS-1), eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Smooth Muscle Myosin
Concentration
0.5 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Alias
AAT4; AV071570; contractile protein; FAA4; KIAA0866; LOW QUALITY PROTEIN: myosin-11; Myh11; myh11 {ECO:0000312; Myosin heavy chain 11; myosin heavy chain 11, smooth muscle; myosin heavy chain 21; myosin heavy chain isoform SMA; myosin heavy chain SMA; myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; myosin-11; RGD:3136}; SM1; SM2; SMHC; SMMHC; smooth muscle myosin heavy chain
Gene Symbols
MYH11
Primary or Secondary
Primary
Content And Storage
4° C
Gene
MYH11
Clone
SMMS-1
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Bovine, Canine, Feline, Human, Rat
Gene Accession No.
P35749, Q63862
Gene ID (Entrez)
101097693, 24582, 4629, 479836, 530050
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Product Type
Antibody
Related Products
Description
- Description: This SMMS-1 monoclonal antibody reacts with both isoforms of the human smooth muscle myosin heavy chain (SM1 and SM2) structural proteins, which are components of the contractile apparatus in smooth muscle cells
- Smooth muscle myosin heavy chains are expressed by myoepithelial cells and also serve as the terminal differentiation marker for smooth muscle cells
- In normal breast tissue, myoepithelial cells compose the outer layer of the lumen lining
- In benign and in situ breast lesions, the intact myoepithelial layer stains with SMMS-1 and the loss of this staining indicates invasive cancer
- This SMMS-1 antibody has also been reported to cross-react with bovine, canine, feline, and rat smooth muscle myosin heavy chains
- Applications Reported: This SMMS-1 antibody has been reported for use in western blotting, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections
- Applications Tested: This SMMS-1 antibody has been tested by western blot on rat heart and immunohistochemistry on formalin-fixed paraffin embedded tissue (with IHC Antigen Retrieval Solution - Low pH (cat
- 00-4955))
- This can be used at less than or equal to 5 μg/mL
- It is recommended that the antibody be titrated for optimal perfomance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- SM-MHC is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells
- Expression of smooth muscle myosin is developmently regulated, appearing early in smooth muscle development, and is specific for smooth muscle development
- Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2.
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Antigen: Smooth Muscle Myosin
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: AAT4; AV071570; contractile protein; FAA4; KIAA0866; LOW QUALITY PROTEIN: myosin-11; Myh11; myh11 {ECO:0000312; Myosin heavy chain 11; myosin heavy chain 11, smooth muscle; myosin heavy chain 21; myosin heavy chain isoform SMA; myosin heavy chain SMA; myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; myosin-11; RGD:3136}; SM1; SM2; SMHC; SMMHC; smooth muscle myosin heavy chain
Gene Symbols: MYH11
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: MYH11
Clone: SMMS-1
Applications: Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Bovine, Canine, Feline, Human, Rat
Gene Accession No.: P35749, Q63862
Gene ID (Entrez): 101097693, 24582, 4629, 479836, 530050
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
Smooth Muscle Myosin
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
AAT4; AV071570; contractile protein; FAA4; KIAA0866; LOW QUALITY PROTEIN: myosin-11; Myh11; myh11 {ECO:0000312; Myosin heavy chain 11; myosin heavy chain 11, smooth muscle; myosin heavy chain 21; myosin heavy chain isoform SMA; myosin heavy chain SMA; myosin heavy chain, smooth muscle isoform; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 11, smooth muscle; myosin-11; RGD:3136}; SM1; SM2; SMHC; SMMHC; smooth muscle myosin heavy chain
Gene Symbols:
MYH11
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
MYH11
Clone:
SMMS-1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Bovine, Canine, Feline, Human, Rat
Gene Accession No.:
P35749, Q63862
Gene ID (Entrez):
101097693, 24582, 4629, 479836, 530050
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: Myosin 4
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: 2B myosin heavy chain; AI506973; fast myosin heavy chain 2B; LOW QUALITY PROTEIN: myosin-4; MHC; MHC2B; Minimsc; Minmus; MM; MYH1; MYH2B; MYH-2B; myh4; MyHC IIb isoform; myHC-2b; MyHC-IIb; Myhsf; myosin heavy chain; myosin heavy chain 1; myosin heavy chain 2b; myosin heavy chain 2X; myosin heavy chain 4; Myosin heavy chain IIb; myosin heavy chain IIb isoform; myosin heavy chain isoform 2b; myosin heavy chain type IIb; Myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 4, skeletal muscle; myosin-4; unnamed protein product
Gene Symbols: MYH4
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: MYH4
Clone: MF20
Applications: Immunocytochemistry, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Rabbit, Rat
Gene Accession No.: Q076A5, Q28641, Q29RW1, Q5SX39, Q9Y623
Gene ID (Entrez): 100009548, 100125991, 100726456, 17884, 360543, 408020, 4622, 468396, 479502
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
Myosin 4
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
2B myosin heavy chain; AI506973; fast myosin heavy chain 2B; LOW QUALITY PROTEIN: myosin-4; MHC; MHC2B; Minimsc; Minmus; MM; MYH1; MYH2B; MYH-2B; myh4; MyHC IIb isoform; myHC-2b; MyHC-IIb; Myhsf; myosin heavy chain; myosin heavy chain 1; myosin heavy chain 2b; myosin heavy chain 2X; myosin heavy chain 4; Myosin heavy chain IIb; myosin heavy chain IIb isoform; myosin heavy chain isoform 2b; myosin heavy chain type IIb; Myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 4, skeletal muscle; myosin-4; unnamed protein product
Gene Symbols:
MYH4
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
MYH4
Clone:
MF20
Applications:
Immunocytochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Bovine, Canine, Chicken, Chimpanzee, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Rabbit, Rat
Gene Accession No.:
Q076A5, Q28641, Q29RW1, Q5SX39, Q9Y623
Gene ID (Entrez):
100009548, 100125991, 100726456, 17884, 360543, 408020, 4622, 468396, 479502
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD265 (RANK)
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Alias: CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Gene Symbols: TNFRSF11A
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: TNFRSF11A
Clone: R12-31
Applications: Flow Cytometry
Conjugate: Unconjugated
Host Species: Rat
Target Species: Mouse
Gene Accession No.: O35305
Gene ID (Entrez): 21934
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD265 (RANK)
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Alias:
CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Gene Symbols:
TNFRSF11A
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
TNFRSF11A
Clone:
R12-31
Applications:
Flow Cytometry
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
O35305
Gene ID (Entrez):
21934
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: DYKDDDDK Tag
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: __
Gene Alias: DDDDK; DDDDK epitope tag; ECS epitope tag; ECS tag; FLAG; FLAG Tag
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: __
Clone: FG4R
Applications: __
Conjugate: Unconjugated
Host Species: Mouse
Target Species: __
Gene Accession No.: __
Gene ID (Entrez): __
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
DYKDDDDK Tag
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
__
Gene Alias:
DDDDK; DDDDK epitope tag; ECS epitope tag; ECS tag; FLAG; FLAG Tag
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
__
Clone:
FG4R
Applications:
__
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
__
Gene Accession No.:
__
Gene ID (Entrez):
__
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Product Type:
Antibody