7069698

PAX6 Monoclonal Antibody (AD2.38), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

PAX6

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

1500038E17Rik; AEY11; AN; AN2; Aniridia; aniridia type II protein; D11S812E; Dey; Dickie's small eye; FVH1; Gsfaey11; Keratitis; MGC17209; MGDA; oculorhombin; paired box 6; paired box gene 6; Paired Box Gene-6; paired box homeotic gene 6; paired box homeotic gene-6; paired box protein Pax-6; Pax6; Pax-6; PAX6 protein; Sey; small eye; transcription factor; WAGR

Gene Symbols

PAX6

Primary or Secondary

Primary

Content And Storage

4° C

Gene

PAX6

Clone

AD2.38

Applications

Immunocytochemistry, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Chicken, Human, Mouse, Rat

Gene Accession No.

P26367, P47237, P63015, P63016

Gene ID (Entrez)

18508, 25509, 395943, 5080

Isotype

IgG1

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: This AD2.38 monoclonal antibody reacts with human, mouse, and rat Pax6
  • This 47-kDa transcription factor is expressed during embryonic neurogenesis in the brain and central nervous system, as well as in neuroepithelial cells of the retina
  • Pax6 is involved in development of the eyes, nose, central nervous system, pancreas, and pituitary gland
  • Studies also demonstrate that Pax6 is crucial for alpha-cell differentiation and glucagon biosynthesis in the pancreas
  • Mutation of Pax6 results in eye disorders such as aniridia in humans and Small eye in mice
  • Applications Reported: This AD2.38 antibody has been reported for use in immunoblotting (WB) and immunocytochemistry
  • Applications Tested: This AD2.38 antibody has been tested by immunocytochemistry of fixed and permeabilized MV+ cells
  • This antibody can be used at less than or equal to 5 μg/mL
  • It is recommended that this antibody be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Aggregation: Less than 10%, as determined by HPLC
  • Filtration: 0.2 μm post-manufacturing filtered
  • This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd
  • In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain
  • Both domains are known to bind DNA, and function as regulators of gene transcription
  • This gene is expressed in the developing nervous system, and in developing eyes
  • Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly
  • Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.

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7069698

Mouse Monoclonal Antibody...


Antigen:
PAX6

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
1500038E17Rik; AEY11; AN; AN2; Aniridia; aniridia type II protein; D11S812E; Dey; Dickie's small eye; FVH1; Gsfaey11; Keratitis; MGC17209; MGDA; oculorhombin; paired box 6; paired box gene 6; Paired Box Gene-6; paired box homeotic gene 6; paired box homeotic gene-6; paired box protein Pax-6; Pax6; Pax-6; PAX6 protein; Sey; small eye; transcription factor; WAGR

Gene Symbols:
PAX6

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
PAX6

Clone:
AD2.38

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Chicken, Human, Mouse, Rat

Gene Accession No.:
P26367, P47237, P63015, P63016

Gene ID (Entrez):
18508, 25509, 395943, 5080

Isotype:
IgG1

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD284 (TLR4)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Gene Symbols:
TLR4

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
TLR4

Clone:
HTA125

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O00206

Gene ID (Entrez):
7099

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
HLA-DR

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
AI323765; BLA-DRB3; BOLA-DRA; BoLA-DR-alpha; BoLA-DRB; BOLA-DRB3; BoLA-DRB3 protein; BoLA-DRB3.2; Bota-DRB01; Bota-DRB02; Bota-DRB04; Bota-DRB07; Bota-DRB21; Bota-DRB22; bovine leukocyte antigen; Cd74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; Clone P2-beta-3; DASS-397D15.1; DHLAG; dinucleotide microsatellite; DLA class II histocompatibility antigen, DR-1 beta chain; DLA DRBB1 beta chain; DLA-DR beta; DLA-DRB1; DLA-DRBB1; DR beta-5; DR beta-chain antigen binding domain; DR-16; DR2-beta-2; DR4; DR-4; DR7; DR9; DR-9; DRB; DRB1; DRB1 transplantation antigen; DRB3; DRB4; DRBB1; DR-beta chain; DR-beta chain MHC class II; DRw10; Dw2; DW2.2/DR2.2; E-alpha-f; FLJ51114; FLJ75017; FLJ76359; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2Ea; H2-Ea; H2-Ea-ps; H2-IE-alpha; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility antigen HLA-DR alpha; histocompatibility complex, class II, DR beta 3; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLA class II histocompatibility antigen, DR alpha chain; HLA class II histocompatibility antigen, DR beta 3 chain; HLA class II histocompatibility antigen, DR beta 4 chain; HLA class II histocompatibility antigen, DR beta 5 chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DR-5 beta chain; HLA class II histocompatibility antigen, DRB1-15 beta chain; HLA class II histocompatibility antigen, DRB1-16 beta chain; HLA class II histocompatibility antigen, DRB1-3 chain; HLA class II histocompatibility antigen, DRB1-7 beta chain; HLA class II histocompatibility antigen, DRB1-9 beta chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR1B; HLA-DR3B; HLA-DR4B; HLA-DRA; HLA-DRA1; HLA-DRB; HLA-DRB1; HLA-DRB2; HLA-DRB3; HLA-DRB4; HLA-DRB5; HLA-DR-gamma; human leucocyte antigen DRB1; human leucocyte antigen DRB3; human leucocyte antigen DRB4; human leucocyte antigen DRB5; ia antigen-associated invariant chain; Ia3; Ia-3; Ia-associated invariant chain; Ia-GAMMA; I-E alpha MHC class II; I-Ealpha; II; integral membrane glycoprotein; invariant gamma chain; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; LA-DRB; leukocyte antigen; leukocyte antigen class II; leukocyte antigen DRB3; lymphocyte antigen DRB1; major histocompatibility complex class II DR-beta chain; major histocompatibility complex, class II, DR alpha; major histocompatibility complex, class II, DR alpha precursor; major histocompatibility complex, class II, DR beta 1; major histocompatibility complex, class II, DR beta 3; major histocompatibility complex, class II, DR beta 4; major histocompatibility complex, class II, DR beta 4 precursor; major histocompatibility complex, class II, DR beta 5; major histocompatibility complex, class II, DRB3; MHC cell surface glycoprotein; MHC class I antigen; MHC class II antigen; MHC class II antigen beta chain; MHC class II antigen BoLA-DRB3; MHC class II antigen DR beta 3 chain; MHC class II antigen DRA; MHC class II antigen DRB1*15; MHC class II antigen DRB1*16; MHC class II antigen DRB1*3; MHC class II antigen DRB1*9; MHC class II antigen DRB3; MHC class II antigen DRB4; MHC class II antigen DRB5; MHC class II antigen E alpha; MHC class II antigen HLA-DR-beta; MHC class II DLA DRB1 beta chain; MHC class II DLA-DRB; MHC class II DLA-DR-beta-1; MHC class II DR beta 1; MHC class II DR beta chain; MHC class II DR beta-chain; MHC class II DR-ALPHA

Gene Symbols:
CD74, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
HLA-DRB4

Clone:
LN3

Applications:
Flow Cytometry, Immunohistochemistry (Frozen)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01903, P01911, P04233, P13762, P79483, Q30154

Gene ID (Entrez):
3122, 3123, 3125, 3126, 3127, 972

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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7069714

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Antigen:
FOXJ1

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
FKHL13; FKHL-13; fork head homologue 4; forkhead box J1; forkhead box protein J1; forkhead transcription factor HFH-4; forkhead-like 13; forkhead-related protein FKHL13; Foxj1; Hepatocyte nuclear factor 3 forkhead homolog 4; Hfh4; HFH-4; HNF-3/forkhead homolog 4; MGC35202

Gene Symbols:
FOXJ1

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
FOXJ1

Clone:
2A5

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
Q61660, Q92949

Gene ID (Entrez):
15223, 2302

Isotype:
IgG1

Purification Method:
Affinity chromatography

Product Type:
Antibody