7092205

CD223 (LAG-3) Monoclonal Antibody (3DS223H), FITC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD223 (LAG-3)

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias

Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Gene Symbols

LAG3

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

Clone

3DS223H

Applications

Flow Cytometry

Conjugate

FITC

Host Species

Mouse

Target Species

Human

Gene Accession No.

P18627

Gene ID (Entrez)

3902

Immunogen

hCD223-FC PFA 4%

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

LAG3

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Description

  • Description: This 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3)
  • LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
  • LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
  • Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
  • CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
  • Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells)
  • This 3DS223H antibody will recognize a formaldehyde-fixed epitope
  • Applications Reported: This 3DS223H antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 3DS223H antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells
  • This can be used at 5 μL (0.06 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
  • LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
  • Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
  • CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
  • Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).

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Show Difference

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7092205

Mouse Monoclonal Antibody...


Antigen:
CD223 (LAG-3)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Gene Symbols:
LAG3

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
3DS223H

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P18627

Gene ID (Entrez):
3902

Immunogen:
hCD223-FC PFA 4%

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
LAG3

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Antigen:
CD366 (TIM3)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3

Gene Symbols:
Havcr2

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
F38-2E2

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q8TDQ0

Gene ID (Entrez):
84868

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Havcr2

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Mouse Monoclonal Antibody...


Antigen:
CD366 (TIM3)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3

Gene Symbols:
Havcr2

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
F38-2E2

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q8TDQ0

Gene ID (Entrez):
84868

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Havcr2

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Antigen:
Armenian Hamster IgG

Concentration:
0.5 mg/mL

Classification:
__

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
IgG; Immunoglobulin G; ImmunoglobulinG

Gene Symbols:
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Isotype:
IgG

Purification Method:
Affinity chromatography

Product Type:
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Clone:
eBio299Arm

Applications:
Control, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry

Conjugate:
FITC

Host Species:
Armenian Hamster

Target Species:
Not Applicable

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
__

Primary or Secondary:
Isotype Control (Primary)

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
__