7182753
Fc gamma RI/CD64, Rabbit anti-Human, Clone: H22, Novus Biologicals™
Rabbit Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Fc gamma RI/CD64
Concentration
1 mg/mL
Applications
Flow Cytometry, ELISA
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Alias
CD64 antigen, Fc fragment of IgG, high affinity Ia, receptor (CD64), FCG1, Fc-gamma receptor I B2, Fc-gamma RI, Fc-gamma RIA, FcgammaRIa, FCGR1, FcRI, FLJ18345, high affinity Ia, receptor for (CD64), high affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I
Gene Symbols
FCGR1A
Isotype
IgG κ
Purification Method
Protein A purified
Test Specificity
This immunotoxin is specific for human Fc gamma RI/CD64, and specifically an epitope outside the Fc binding domain. The binding activity of the VH/VL antibody format was unaffected by fusion of the m22(scFv) coding regions to the truncated ETA coding sequences
Clone
H22
Dilution
Flow Cytometry, Competitive ELISA
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Formulation
PBS
Gene ID (Entrez)
2209
Immunogen
This recombinant antibody was prepared by cloning the single chain fragment (scFv) derived from the murine anti-human Fc gamma RI/CD64 mAb m22 into the bacterial expression vector pBM1.1, and fusing it to a deletion mutant of Pseudomonas exotoxin A.
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Related Products
Description
- Fc gamma RI/CD64 Monoclonal specifically detects Fc gamma RI/CD64 in Human samples
- It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Competitive ELISA.
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Antigen: Fc gamma RI/CD64
Concentration: 1 mg/mL
Applications: Flow Cytometry, ELISA
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Alias: CD64 antigen, Fc fragment of IgG, high affinity Ia, receptor (CD64), FCG1, Fc-gamma receptor I B2, Fc-gamma RI, Fc-gamma RIA, FcgammaRIa, FCGR1, FcRI, FLJ18345, high affinity Ia, receptor for (CD64), high affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I
Gene Symbols: FCGR1A
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: This immunotoxin is specific for human Fc gamma RI/CD64, and specifically an epitope outside the Fc binding domain. The binding activity of the VH/VL antibody format was unaffected by fusion of the m22(scFv) coding regions to the truncated ETA coding sequences
Clone: H22
Dilution: Flow Cytometry, Competitive ELISA
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS
Gene ID (Entrez): 2209
Immunogen: This recombinant antibody was prepared by cloning the single chain fragment (scFv) derived from the murine anti-human Fc gamma RI/CD64 mAb m22 into the bacterial expression vector pBM1.1, and fusing it to a deletion mutant of Pseudomonas exotoxin A.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigen:
Fc gamma RI/CD64
Concentration:
1 mg/mL
Applications:
Flow Cytometry, ELISA
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Alias:
CD64 antigen, Fc fragment of IgG, high affinity Ia, receptor (CD64), FCG1, Fc-gamma receptor I B2, Fc-gamma RI, Fc-gamma RIA, FcgammaRIa, FCGR1, FcRI, FLJ18345, high affinity Ia, receptor for (CD64), high affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I
Gene Symbols:
FCGR1A
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
This immunotoxin is specific for human Fc gamma RI/CD64, and specifically an epitope outside the Fc binding domain. The binding activity of the VH/VL antibody format was unaffected by fusion of the m22(scFv) coding regions to the truncated ETA coding sequences
Clone:
H22
Dilution:
Flow Cytometry, Competitive ELISA
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Formulation:
PBS
Gene ID (Entrez):
2209
Immunogen:
This recombinant antibody was prepared by cloning the single chain fragment (scFv) derived from the murine anti-human Fc gamma RI/CD64 mAb m22 into the bacterial expression vector pBM1.1, and fusing it to a deletion mutant of Pseudomonas exotoxin A.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigen: B7-1/CD80
Concentration: 1 mg/mL
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Functional Assay, Blocking Assay
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Alias: Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen), CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80
Gene Symbols: CD80
Isotype: IgG λ
Purification Method: Protein A purified
Test Specificity: Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.
Clone: IDEC-114 (Galiximab)
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Functional, Block/Neutralize
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS
Gene ID (Entrez): 941
Immunogen: Galiximab was prepared by immunizing cynomolgus monkeys with recombinant B7-1/CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigen:
B7-1/CD80
Concentration:
1 mg/mL
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Functional Assay, Blocking Assay
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Alias:
Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen), CD80 antigen, CD80 molecule, costimulatory factor CD80, costimulatory molecule variant IgV-CD80, CTLA-4 counter-receptor B7.1, T-lymphocyte activation antigen CD80
Gene Symbols:
CD80
Isotype:
IgG λ
Purification Method:
Protein A purified
Test Specificity:
Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.
Clone:
IDEC-114 (Galiximab)
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Functional, Block/Neutralize
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Formulation:
PBS
Gene ID (Entrez):
941
Immunogen:
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant B7-1/CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigen: CD40/TNFRSF5
Concentration: 1 mg/mL
Applications: ELISA, Functional Assay, Blocking Assay
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Alias: B cell surface antigen CD40, B-cell surface antigen CD40, Bp50B cell-associated molecule, CD40 antigen, CD40 molecule, TNF receptor superfamily member 5, CD40 type II isoform, CD40L receptor, CDw40, MGC9013, nerve growth factor receptor-related B-lymphocyte activation molecule, p50, TNFRSF5CD40 antigen (TNF receptor superfamily member 5), tumor necrosis factor receptor superfamily member 5, tumor necrosis factor receptor superfamily, member 5
Gene Symbols: CD40
Isotype: IgG λ
Purification Method: Protein A purified
Test Specificity: A54 binds specifically to the D1 domain of CD40/TNFRSF5 (and can only bind to the intact i.e. non-truncated version of CD40/TNFRSF5 and when an AD2 peptide tag has not been added) and can recognize CD40/TNFRSF5 on a B cell line (BJAB). This scFv binds to CD40/TNFRSF5 (immobilized by amine coupling) with a KD within the range of 40nM. CD40/TNFRSF5 is a glycoprotein of the TNFR superfamily and is expressed on all mature B cells, dendritic cells, activated monocytes, some endothelial cells and some epithelium including the thymus. CD40/TNFRSF5 binds to the membrane protein CD154 of the TNF superfamily and this interaction is required for the seconfary immune responses and germinal centre formation.
Clone: A54 scFv
Dilution: ELISA, Functional, Block/Neutralize
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS
Gene ID (Entrez): 958
Immunogen: A54 human anti-CD40/TNFRSF5 scFv was selected from the n-CoDeR phage display library after 4 rounds of selections using biotinylated CD40-Fcgamma fusion protein as bait and subsequent capture of bound phages on streptavidin-caoted magnetic beads.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigen:
CD40/TNFRSF5
Concentration:
1 mg/mL
Applications:
ELISA, Functional Assay, Blocking Assay
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Alias:
B cell surface antigen CD40, B-cell surface antigen CD40, Bp50B cell-associated molecule, CD40 antigen, CD40 molecule, TNF receptor superfamily member 5, CD40 type II isoform, CD40L receptor, CDw40, MGC9013, nerve growth factor receptor-related B-lymphocyte activation molecule, p50, TNFRSF5CD40 antigen (TNF receptor superfamily member 5), tumor necrosis factor receptor superfamily member 5, tumor necrosis factor receptor superfamily, member 5
Gene Symbols:
CD40
Isotype:
IgG λ
Purification Method:
Protein A purified
Test Specificity:
A54 binds specifically to the D1 domain of CD40/TNFRSF5 (and can only bind to the intact i.e. non-truncated version of CD40/TNFRSF5 and when an AD2 peptide tag has not been added) and can recognize CD40/TNFRSF5 on a B cell line (BJAB). This scFv binds to CD40/TNFRSF5 (immobilized by amine coupling) with a KD within the range of 40nM. CD40/TNFRSF5 is a glycoprotein of the TNFR superfamily and is expressed on all mature B cells, dendritic cells, activated monocytes, some endothelial cells and some epithelium including the thymus. CD40/TNFRSF5 binds to the membrane protein CD154 of the TNF superfamily and this interaction is required for the seconfary immune responses and germinal centre formation.
Clone:
A54 scFv
Dilution:
ELISA, Functional, Block/Neutralize
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Formulation:
PBS
Gene ID (Entrez):
958
Immunogen:
A54 human anti-CD40/TNFRSF5 scFv was selected from the n-CoDeR phage display library after 4 rounds of selections using biotinylated CD40-Fcgamma fusion protein as bait and subsequent capture of bound phages on streptavidin-caoted magnetic beads.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigen: EDAR
Concentration: 1 mg/mL
Applications: Western Blot, ELISA, Blocking Assay
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse, Rat, Canine, Chicken
Gene Alias: Anhidrotic ectodysplasin receptor 1, DLED3, Ectodermal dysplasia receptor, ectodysplasin 1, anhidrotic receptor, ectodysplasin A receptor, Ectodysplasin-A receptor, ED1R, ED5, EDA1R, EDA3EDA-A1 receptor, EDA-A1R, Edar, FLJ94390, HRM1, mouse, homolog of, tumor necrosis factor receptor superfamily member EDAR
Gene Symbols: EDAR
Isotype: IgG κ
Purification Method: Protein A purified
Test Specificity: EDAR12 recognises and binds to CRD1 of the extracellular domain of mouse EDAR. EDAR3 cross-reacts with EDAR derived from human, dog, rat and chicken when EDAR is fused to the glycosylphosphatidylinositol anchor of TRAILR3. EDAR is the receptor for the TNF family ligand EDA1, which is a type II transmembrane protein possessing a collagen-like domain and a C-terminal TNF-homology domain. EDAR is important for the correct development of skin appendages including hair, teeth and eccrine sweat glands. LoF mutations in the Eda gene is known to cause XLHED (X-linked hypohidrotic ectodermal dysplasia), and results in abnormal development.
Clone: EDAR12
Dilution: Western Blot, ELISA, Surface Plasmon Resonance, Block/Neutralize
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Formulation: PBS
Gene ID (Entrez): 10913
Immunogen: EDAR12 was prepared by immunixzing female OVE1B mice (with the Edar gene deleted) subcutaneously with mouse EDAR-Fc and positive hybridoma clones were screened for binding mEDAR by ELISA.
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigen:
EDAR
Concentration:
1 mg/mL
Applications:
Western Blot, ELISA, Blocking Assay
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse, Rat, Canine, Chicken
Gene Alias:
Anhidrotic ectodysplasin receptor 1, DLED3, Ectodermal dysplasia receptor, ectodysplasin 1, anhidrotic receptor, ectodysplasin A receptor, Ectodysplasin-A receptor, ED1R, ED5, EDA1R, EDA3EDA-A1 receptor, EDA-A1R, Edar, FLJ94390, HRM1, mouse, homolog of, tumor necrosis factor receptor superfamily member EDAR
Gene Symbols:
EDAR
Isotype:
IgG κ
Purification Method:
Protein A purified
Test Specificity:
EDAR12 recognises and binds to CRD1 of the extracellular domain of mouse EDAR. EDAR3 cross-reacts with EDAR derived from human, dog, rat and chicken when EDAR is fused to the glycosylphosphatidylinositol anchor of TRAILR3. EDAR is the receptor for the TNF family ligand EDA1, which is a type II transmembrane protein possessing a collagen-like domain and a C-terminal TNF-homology domain. EDAR is important for the correct development of skin appendages including hair, teeth and eccrine sweat glands. LoF mutations in the Eda gene is known to cause XLHED (X-linked hypohidrotic ectodermal dysplasia), and results in abnormal development.
Clone:
EDAR12
Dilution:
Western Blot, ELISA, Surface Plasmon Resonance, Block/Neutralize
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Formulation:
PBS
Gene ID (Entrez):
10913
Immunogen:
EDAR12 was prepared by immunixzing female OVE1B mice (with the Edar gene deleted) subcutaneously with mouse EDAR-Fc and positive hybridoma clones were screened for binding mEDAR by ELISA.
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.