7190537
Phospho-SMAD2 (Ser467) Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Phospho-SMAD2 (Ser467)
Applications
Dot Blot, ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q15796
Gene ID (Entrez)
4087
Primary or Secondary
Primary
Product Type
Antibody
Concentration
1 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
7120426M23Rik; BOS_22266; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; SMAD2; Smad-2; Smad2Deltaexon3
Gene Symbols
SMAD2
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
SMAD2
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Anti-SMAD2 pS467 antibody is directed against the phosphorylated form of human Smad2 protein at the pS467 residue
- Reactivity with non-phosphorylated human Smad2 is minimal by ELISA and dot blot
- A BLAST analysis was used to suggest cross-reactivity with Smad2 protein based on 100% homology with the immunizing sequence to human, mouse, rat, orangutan, zebrafish, and bovine
- Reactivity against homologues from other sources is not known
- SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
- SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
- Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
- In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
- The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
- The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
- SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
- Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.
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Antigen: Phospho-SMAD2 (Ser467)
Applications: Dot Blot, ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q15796
Gene ID (Entrez): 4087
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: 7120426M23Rik; BOS_22266; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; SMAD2; Smad-2; Smad2Deltaexon3
Gene Symbols: SMAD2
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: SMAD2
Antigen:
Phospho-SMAD2 (Ser467)
Applications:
Dot Blot, ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q15796
Gene ID (Entrez):
4087
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
7120426M23Rik; BOS_22266; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; Mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; SMAD2; Smad-2; Smad2Deltaexon3
Gene Symbols:
SMAD2
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
SMAD2
Antigen: alpha-Tubulin
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bovine, Chicken, Human, Mouse, Rat
Gene Accession No.: P05213, P0DPH7, P68363, P68366, P68368, P68369, P68370, P68373, P81947, P81948, Q32KN8, Q3ZCJ7, Q5XIF6, Q6AYZ1, Q6P9V9, Q6PEY2, Q71U36, Q9BQE3
Gene ID (Entrez): 100857247, 100857858, 10376, 112714, 22142, 22143, 22145, 22146, 300218, 316531, 404053, 421169, 429035, 500929, 504244, 534900, 539882, 64158, 7277, 7278, 777775, 7846, 84790
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1.1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: 1t; a1t; ALPHA 84C; alpha tubulin; alpha tubulin 84B; alpha[[1]] tubulin; alpha[[1]]-tubulin; alpha1; alpha1 tubulin; alpha1t; alpha1tub; alpha1tub84B; alpha1-tubulin; alpha84B; alphaT; alphat-1; alphatub; alpha-Tub; alphaTub1; alphatub84; alphaTub84B; alpha-tub84B; alphaTub84B-PA; alphatubulin; alpha-tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3D; Alpha-tubulin 3E; Alpha-tubulin 4; Alpha-tubulin 6; alphaTubulin 84B; alpha-tubulin 84B; alpha-Tubulin at 84B; Alpha-tubulin I; Alpha-tubulin II; Alpha-tubulin III; Alpha-tubulin isotype M-alpha-1; Alpha-tubulin isotype M-alpha-2; Alpha-tubulin isotype M-alpha-4; Alpha-tubulin isotype M-alpha-6; alpha-tubulin TUB1; Alpha-tubulin ubiquitous; alphaTubulin84B; alpha-tubulin84B; ALS22; anon-EST:Liang-1.59; anon-EST:Liang-2.30; aTub84B; a-tub84B; bA408E5.3; b-alpha-1; bcm948; BEST:LD32507; BOS_16828; BOS_16831; BOS_2117; BOS_5053; BOS_5055; cb944; CG1913; CG1913 gene product from
Gene Symbols: Tuba1a, Tuba1b, TUBA1C, TUBA3C, TUBA3E, TUBA4A
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Tuba1a
Antigen:
alpha-Tubulin
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bovine, Chicken, Human, Mouse, Rat
Gene Accession No.:
P05213, P0DPH7, P68363, P68366, P68368, P68369, P68370, P68373, P81947, P81948, Q32KN8, Q3ZCJ7, Q5XIF6, Q6AYZ1, Q6P9V9, Q6PEY2, Q71U36, Q9BQE3
Gene ID (Entrez):
100857247, 100857858, 10376, 112714, 22142, 22143, 22145, 22146, 300218, 316531, 404053, 421169, 429035, 500929, 504244, 534900, 539882, 64158, 7277, 7278, 777775, 7846, 84790
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1.1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
1t; a1t; ALPHA 84C; alpha tubulin; alpha tubulin 84B; alpha[[1]] tubulin; alpha[[1]]-tubulin; alpha1; alpha1 tubulin; alpha1t; alpha1tub; alpha1tub84B; alpha1-tubulin; alpha84B; alphaT; alphat-1; alphatub; alpha-Tub; alphaTub1; alphatub84; alphaTub84B; alpha-tub84B; alphaTub84B-PA; alphatubulin; alpha-tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3D; Alpha-tubulin 3E; Alpha-tubulin 4; Alpha-tubulin 6; alphaTubulin 84B; alpha-tubulin 84B; alpha-Tubulin at 84B; Alpha-tubulin I; Alpha-tubulin II; Alpha-tubulin III; Alpha-tubulin isotype M-alpha-1; Alpha-tubulin isotype M-alpha-2; Alpha-tubulin isotype M-alpha-4; Alpha-tubulin isotype M-alpha-6; alpha-tubulin TUB1; Alpha-tubulin ubiquitous; alphaTubulin84B; alpha-tubulin84B; ALS22; anon-EST:Liang-1.59; anon-EST:Liang-2.30; aTub84B; a-tub84B; bA408E5.3; b-alpha-1; bcm948; BEST:LD32507; BOS_16828; BOS_16831; BOS_2117; BOS_5053; BOS_5055; cb944; CG1913; CG1913 gene product from
Gene Symbols:
Tuba1a, Tuba1b, TUBA1C, TUBA3C, TUBA3E, TUBA4A
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Tuba1a
Antigen: Deoxyribonuclease I
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: HRP
Host Species: Rabbit
Target Species: Bovine
Gene Accession No.: P00639
Gene ID (Entrez): 282217
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias: AI788650; Deoxyribonuclease 1; Deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; DNASE1; DNaseI; DNL 1; Dnl1; Dornase alfa; DRNI; FLJ38093; human urine deoxyribonuclease I
Gene Symbols: DNASE1
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: DNASE1
Antigen:
Deoxyribonuclease I
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
HRP
Host Species:
Rabbit
Target Species:
Bovine
Gene Accession No.:
P00639
Gene ID (Entrez):
282217
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
AI788650; Deoxyribonuclease 1; Deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; DNASE1; DNaseI; DNL 1; Dnl1; Dornase alfa; DRNI; FLJ38093; human urine deoxyribonuclease I
Gene Symbols:
DNASE1
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
DNASE1
Antigen: IFN Induced GTPase-like Protein
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: __
Gene ID (Entrez): 225594
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 86.5 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.5M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: Gm4841
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Gm4841
Antigen:
IFN Induced GTPase-like Protein
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
__
Gene ID (Entrez):
225594
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
86.5 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.5M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
Gm4841
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Gm4841